J Dhaka Medical College, Vol. 21, No. 2, October, 2012, Page 152-155 DOI: http://dx.doi.org/10.3329/jdmc.v21i2.15337

Abstract

Background: Infertility is defined as the failure in pregnancy after one year of unprotected intercourse. Several centers have reported different causes of infertility. The most common causes of infertility include: Female factors such as ovulation dysfunction and tubal factor; male factors like sperm disturbance as well as ; both male and female factors and unexplained infertility. The aim of this study was to find out the etiologic factors of infertility in BSMMU (Bangabandhu Sheik Mujib Medical University, Dhaka, Bangladesh)Methods: This cross sectional study was done at the Out Patient Department (OPD) of infertility in BSMMU during the period of December 2004 to March 2005. One hundred infertile couples with necessary investigations were reviewed for the study. Results: In this study the frequency of primary and secondary infertility was 56% and 44% respectively. Among 100 couples 57% had female factor, 25% had both male and female factors and in 3% had male factor and in 15% of couple, the causes of infertility were unknown. Among women, different infertility factors included: Tubal factor 33%, Ovarian factor 12% and endometriosis 11%. In this study tubal blockage were detected in 50% cases of female secondary subfertility following Menstruation Regulation (M/R). Result showed 82% of men had normal spermogram 28%, had sperm disturbance including Oligospermia, Asthenospermia, Oligoasthenospermia and teratospermia. Conclusion: Although female factor was the most common cause of infertility in BSMMU, we can not conclude that this factor is the most common causes of infertility in Bangladesh. Since this centre is considered as referral centre especially for female infertility. We suggest performance of similar researches with big sample size in different institution to evaluate most common causes of infertility in Bangladesh.DOI: http://dx.doi.org/10.3329/jom.v14i2.18460 J Medicine 2013, 14(2): 110-113

No abstract

Background: Vulvar cancer is one of the rare malignancies of the female genital tract. Vulvar cancer is predominantly a disease of post-menopausal multiparous women. Objective: The aim of this study was to analyse and report the clinico-pathological features and treatment modalities of patients with vulvar cancer treated at National Institute of Cancer Research and Hospital (NICR&H), Dhaka, Bangladesh. Methods: This was a cross- sectional observational study conducted among 96 vulvar cancer cases treated at National Institute of Cancer Research and Hospital (NICR&H), Dhaka, Bangladesh from 2015 to 2020. The medical records of patients with vulvar cancer were retrospectively reviewed after obtaining approval from the Institutional Review Board (IRB). Clinical details of all vulvar cancer patients and treatment given were collected from the hospital records and were reviewed retrospectively. Results: A total of 96 patients with vulvar cancer were included for this retrospective analysis. The median age was 50 years (range, 12- 85 years) with a mean (±SD) of 50.50±15.12 years. Stages of the disease were: stage I: 27.1% patients; stage II: 22.9% patients; stage III: 30.3% patients; stage IV: 16.7% patients; and unknown stage: 3.1% patient as per International Federation of Gynecology and Obstetrics (FIGO) staging system. Histopathologically, squamous cell carcinoma (SCC) was the most common histologic type (84.4%) followed by adenocarcinoma (5.2%), melanoma (4.2%), basal cell carcinoma (3.1%), and others (3.1%). Most of the patients (45.8%) were treated by surgery with or without adjuvant radiotherapy. About 24.0% of patients were treated primarily by radiotherapy and/or chemo-radiotherapy. Conclusion: Management of vulvar cancer requires multidisciplinary team approach, which is available only in tertiary care centres. The treatment of vulvar cancer is surgery, radiotherapy, chemo- radiotherapy or a combination therapy. Treatment should be individualised based on lesions location and histological type. Bangladesh Med Res Counc Bull 2022; 48(1): 64-70