Adoptive immunotherapy is a technically feasible and safe treatment with low toxicity and may demonstrate therapeutic activity in patients with unresectable SCCHN.
Volume 115 Number 2 Scientific Posters P 193 cess. Although some studies suggest ossification of the cochlea can occur in far advanced otosclerosis, we are unaware of previous reports of clinically significant ossification of the cochlear duct by otosclerosis identified during cochlear implantation.We present a patient with obliterative otosclerosis in whom bilateral attempts at stapedectomy and amplification failed. Cochlear implantation was considered and preoperative imaging studies were obtained. High-resolution CT and MRI suggested absence of a fluid-filled basal turn of the cochlea. These findings were confirmed at the time of surgery, necessitating extended drilling of the cochlea until a patent lumen was entered. The full length of a multichannel Nucleus cochlear implant was inserted into the second turn of the left cochlea. This case demonstrates both the extent of neoossification otosclerosis can produce and the importance of MRI as a preoperative adjunct to the traditional highresonance CT evaluation of cochlear implant candidates.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.