Percutaneous bedside twist-drill drainage is a relatively safe and effective first-line management option. These findings may result in potential health cost savings and eliminate perioperative risks related to general anesthetic.
Mean PFV values were found to be smaller in pediatric CMI patients than control patients; this complements earlier studies in adults and supports the present theory concerning the pathophysiological mechanism of CMI. Subtle morphometric differences among asymptomatic and symptomatic patients aged 0-9 years stress the importance of monitoring asymptomatic patients for the onset of symptoms in their adult years. Symptom development in CMI is likely multifactorial and is much more extensive than the degree of cerebellar tonsillar herniation.
Objective: There is no standard protocol to guide the optimal time to resume anti-clotting agents after traumatic brain injury (TBI) in patients with a continued indication for anticoagulation/antiplatelet therapy (AAT). This study develops baseline data supporting a future prospective cohort study. We predict that there will be significantly decreased adverse events when AAT is started on or after Day 7.Methods: A retrospective chart review of 256 patients was performed. Patients admitted to a level I trauma center in West Texas between January 1, 2009, and December 31, 2012, on anti-clotting agents (specifically acetylsalicylic acid, coumadin, and/or clopidogrel) and who suffered a TBI were included. Patient metrics included admission coagulation studies, type of TBI and treatment, and time to continuation of AAT. Outcomes were assessed using follow-up appointment data. The primary outcome was death (mortality). Secondary outcomes included myocardial infarction, stroke, re-bleed, venous thromboembolism, and pneumonia.Results: A total of 256 patients met the inclusion criteria. However, only 85 patients on AAT presented for the six-month follow-up. Time to AAT resumption varied from immediate to 31 days. Out of the 85 patients, 32 patients never resumed AAT, 32 patients were restarted on AAT medication in less than seven days, 10 patients restarted medication between seven and 14 days, and 11 patients restarted AAT in more than 14 days. Adverse events occurred most infrequently in the AAT group resuming therapy between seven and 14 days (10%). Adverse events were most prevalent in the AAT group that never resumed therapy (68.8%).Conclusion: While most studies suggest that the safest time for resuming AAT lies between three and 10 days, our study revealed that adverse events were minimized in patients on AAT between seven and 9.5 days.
first described the caudal displacement of the cerebellar tonsils in 1891 and such abnormality is frequently identified in both young adult and pediatric patients. Clinical presentation can be very variable, ranging from asymptomatic incidental abnormality discovered by imaging for other indications to symptoms arising from raised intracranial pressure, brainstem compression, cerebellar dysfunction, or concomitant spinal cord syrinx. Neuroimaging findings for Chiari I malformation have typically revealed descent of the cerebellar tonsils by 5 mm beyond the foramen magnum into the spinal canal. However, the putative pathoembryology of an underdeveloped para-axial mesoderm 2,3 has lead several authors RÉSUMÉ: Classification de la malformation de Chiari de type 1 symptomatique pour guider la stratégie chirurgicale. Contexte : Les options de traitement des malformations de Chiari de type 1 incluent la décompression de la fosse postérieure (DFP) et certaines techniques comme la laminectomie, l'exploration intradurale et la plastie de la dure-mère. L'intervention chirurgicale peut être modifiée selon les observations du volume de la citerne cérébello-médullaire et de la syringomyélie faites à la neuroimagerie et les observations faites à l'échographie peropératoire (EPO). Méthodes : Nous avons développé un algorithme pour classifier les patients atteints de Chiari de type 1 symptomatique en trois groupes afin de définir l'intervention minimale. En l'absence de syringomyélie, la présence de la citerne cérébello-médullaire est caractéristique du groupe A et son absence est caractéristique du groupe B. Les patients qui ont un syrinx constituent le groupe C. Ceux qui ont une pathologie structurale légère (groupe A) ou un espace adéquat après la DFP (groupe B, EPO normale) devraient être traités seulement par la DFP, contrairement à ceux qui ont une syringomyélie (groupe C) ou un espace inadéquat suite à la DFP (groupe B, EPO anormale) devraient subir une plastie de la dure-mère. Nous avons utilisé cet algorithme chez des patients traités dans la même institution au cours d'une période de 16 ans. Résultats : Vingt-quatre patients atteints d'une malformation de Chiari de type 1 symptomatique ont été divisés en trois groupes dont la répartition selon l'âge, le sexe et l'étendue de l'ectopie amygdalienne était la même. Tous les patients traités selon cet algorithme ont eu une amélioration clinique et radiologique, dont 8 patients du groupe B qui ont subi seulement une DFP (n = 6) ou une DFP avec plastie de la dure-mère (n = 2) sur la base de l'EPO. Conclusion : Le résultat du traitement de la malformation de Chiari de type 1 symptomatique peut être inadéquat si une stratégie conservatrice est utilisée ou s'il survient des complications si une stratégie agressive est utilisée. Cet algorithme utilise la neuroimagerie préopératoire et l'échographie peropératoire pour adapter l'intervention. Le résultat clinique et la résolution du syrinx radiologique ont été excellents chez ces 24 patients. Cet algorithme devrait faire l'objet d...
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