CorrectionS. Halpern et al. Comparison of adenoma detection and miss rate between a novel balloon colonoscope and standard colonoscopy: a randomized tandem study.The authors have requested the following changes:▶ Page 240, "Study End Points", second paragraph, line 17 -18, the sentence "The ratio of balloon colonoscopy additional adenoma detection to the standard colonoscopy miss rate is a measure of the adenoma detection…" was corrected to "The ratio of balloon colonoscopy additional adenoma detection to the miss rate is a measure of the adenoma detection…"▶ Page 241 "Per-lesion adenoma detection and miss rates", third paragraph, line 3 -5, the sentence "The ratio of balloon colonoscopy additional adenoma detection to the standard colonoscopy miss rate was 10.8 (81 %/7.5 %)." was corrected to "The ratio of balloon colonoscopy additional adenoma detection to the miss rate was 10.8 (81 %/7.5 %)."
Background and Aims: Colorectal cancer (CRC) is largely preventable with routine screening and surveillance colonoscopy; however, interval cancers arising from precancerous lesions missed by standard colonoscopy still occur. An increased adenoma detection rate (ADR) has been found to be inversely associated with interval cancers. The G-EYE device includes a reusable balloon integrated at the distal tip of a standard colonoscope, which flattens haustral folds, centralizes the colonoscope's optics, and reduces bowel slippage. The insufflated balloon also aims to enhance visualization of the colon during withdrawal, thereby increasing the ADR. Methods: In this randomized, controlled, international, multicenter study (11 centers), patients (aged !50 years) referred to colonoscopy for screening, surveillance, or changes in bowel habits were randomized to undergo either balloon-assisted colonoscopy by using an insufflated balloon during withdrawal or standard highdefinition colonoscopy. The primary endpoint was the ADR. Results: One thousand patients were enrolled between May 2014 and September 2016 to undergo colonoscopy by experienced endoscopists; 803 were finally analyzed (standard colonoscopy n Z 396; balloon-assisted colonoscopy n Z 407). Baseline parameters were similar in both groups. Balloon-assisted colonoscopy provided a 48.0% ADR compared with 37.5% in the standard colonoscopy group (28% increase; P Z .0027). Additionally, balloonassisted colonoscopy provided for a significant increase in detection of advanced (P Z .0033) flat adenomas (P < .0001) and sessile serrated adenomas/polyps (P Z .0026). Conclusion: Balloon-assisted colonoscopy yielded a higher ADR and increased the detection of advanced, flat, and sessile serrated adenomas/polyps when compared with standard colonoscopy. Improved detection by the G-EYE device could impact the quality of CRC screening by reducing miss rates and consequently reducing interval cancer incidence.
A novel balloon colonoscopy technique detected significantly more adenomas than standard colonoscopy, and missed fewer adenomas. Balloon colonoscopy has the potential to increase the effectiveness of colorectal cancer screening and surveillance colonoscopy.
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