The bespoke software is capable of extracting accurate and repeatable ciliary muscle measurements and is suitable for analysing large data sets.

Purpose. To examine the influence of positional misalignments on intraocular pressure (IOP) measurement with a rebound tonometer. Methods. Using the iCare rebound tonometer, IOP readings were taken from the right eye of 36 healthy subjects at the central corneal apex (CC) and compared to IOP measures using the Goldmann applanation tonometer (GAT). Using a bespoke rig, iCare IOP readings were also taken 2 mm laterally from CC, both nasally and temporally, along with angular deviations of 5 and 10 degrees, both nasally and temporally to the visual axis. Results. Mean IOP ± SD, as measured by GAT, was 14.7 ± 2.5 mmHg versus iCare tonometer readings of 17.4 ± 3.6 mmHg at CC, representing an iCare IOP overestimation of 2.7 ± 2.8 mmHg (P < 0.001), which increased at higher average IOPs. IOP at CC using the iCare tonometer was not significantly different to values at lateral displacements. IOP was marginally underestimated with angular deviation of the probe but only reaching significance at 10 degrees nasally. Conclusions. As shown previously, the iCare tonometer overestimates IOP compared to GAT. However, IOP measurement in normal, healthy subjects using the iCare rebound tonometer appears insensitive to misalignments. An IOP underestimation of <1 mmHg with the probe deviated 10 degrees nasally reached statistical but not clinical significance levels.

The OCT based instrument assessed in this study is able to match and improve on the JCF instrument for the measurement of total diameter, back optic zone radius and centre thickness for soft contact lenses in temperature controlled saline.

Optical coherence tomography (OCT) is increasingly used in areas such as ophthalmology and contact lens metrology. However, in such cases, image distortion can occur due to the non-planar nature of the measured sample. Postprocessing algorithms can be implemented to correct this distortion. Here we present an OCT phantom designed to confirm the validity of post-processing algorithms used for measuring curved surfaces. A multi-purpose OCT phantom has been created within a fused silica plano-convex lens using the direct femtosecond laser writing technique. This phantom can be used to calibrate and quantitatively assess the performance (e.g. resolution, sensitivity and distortion) of OCT systems and associated post-processing algorithms for curved structures such as lenses. This novel OCT phantom has been characterized using an optical microscope and OCT systems.

No abstract