Electrochemical detection (ECD) technique has been deemed to be an effective method for detection. However, low sensitivity and poor anti-interference ability restrict its widespread use in quercetin detection. Herein, a coral reef-like Pt-decorated MXene composite is developed to construct a sensitive Pt-MXene/GCE electrode to achieve accurate detection for quercetin. The multilayer structure of MXene in the complex provides sufficient active sites for the electrochemical reaction and promotes electron transfer, leading to reduction in electrochemical impedance. The electrochemical behavior of quercetin on the Pt-MXene/GCE electrode reveals that the electrochemical redox process involves the participation of the two-electron/doubleproton reaction process. As expected, the Pt-MXene/GCE electrode exhibits excellent stability, repeatability, reproducibility, and selectivity and shows accurate detection ability in actual application. In addition, the Pt-MXene/GCE electrode possesses a low limit of detection and high sensitivity, which is superior than most of the previous reports. This work provides a promising strategy for selective ECD of quercetin, which would give guidance for the fabrication of a highly selective sensor with outstanding sensitivity.
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