Highlights Penila strangulation required emergency management to preserve the organ function. Each case managed individually according to its clinical finding and operative settings. Management depends on the type and size of constricting object, time after incarceration, degree of injury, available instrument, and experience of the physicians. Different methods and tools may arise due to circumstance and individual cases differences. Surprisingly, there is no erection problem after removing the strangulation.

The risk of urinary tract stone disease is influenced by lifestyle, genetics and diet. Coffee, tea and drinking water source are one dietary factor that influences the urinary volume and urinary solute concentration. This study investigates the influence of coffee, tea and type of drinking water source to the risk of calcium kidney stone disease in Universitas Padjadjaran/Hasan Sadikin Hospital, Bandung West Java Indonesia. A hospital based case control study was conducted in Universitas Padjadjaran/Hasan Sadikin General Hospital from November 2016 to January 2017. 30 urinary tract calcium disease patients and 30 controlled patients were enrolled in this study. Patient characteristic and number of cup of coffee and tea intake as well as source of water were collected using checklist items. Two tailed independent t-tests Mann Whitney U, Chi square test and Fisher Exact Test were used for statistical analysis. The odds ratios for daily tea and daily tea and coffee intake are 0.33 and 0.2 and are statistically significant (P = 0.038 and P = 0.04). This result showed that tea and coffee have influence on the risk of calcium stone disease.

BACKGROUND: Prostate cancer is the second most commonly occurring cancer in adult males worldwide. Androgen deprivation therapy (ADT) is the mainstay treatment for patients with advanced prostate cancer. However, despite the low testosterone level (indicative of ADT success), most advanced prostate cancers progress into an androgen unresponsive or castrate resistant state; such cases are defined as castrate-resistant prostate cancer (CRPC) and were associated with worse outcomes and more rapid prostate cancer progression. This study aimed to compare the value of nadir testosterone level and nadir PSA in CRPC and non-CRPC patients who received ADT. AIM: This study was aimed to compare value of nadir testosterone level and nadir PSA in CRPC and non-CRPC patients who received ADT. METHODS: Prostate cancer patients receiving ADT in dr. Hasan Sadikin Bandung General Hospital in September 2018–September 2020 without previous history of CRPC and surgical castration, and prostate cancer with histopathological confirmation were included to the study. The patients prior had received complete blockade ADT with luteinizing hormone agonist (LHRH) goserelin acetate 10.8 mg injected subcutaneously per 3 months and oral anti-androgen bicalutamide 50 mg orally daily. Testosterone and PSA levels were assessed on 1st, 3rd, 6th, and 12th month. Patients then were grouped into CRPC group and non-CRPC group and further subdivided according testosterone levels (<20 and 20–500 ng/dL). Paired t-test and Chi-square test were used to analyze statistical difference (p < 0.05 deemed significant). RESULTS: Significantly higher baseline PSA (p = 0.002) and nadir PSA (p = 0.013) were found on the CRPC group. Nadir testosterone in CRPC group was higher than non-CRPC group but statistically insignificant (p = 0.849). Time to CRPC is faster in nadir testosterone 20–50 ng/dl group than in <20 ng/dl group but statistically insignificant (p = 0.837). CONCLUSION: Prostate cancer patients who had high baseline PSA and nadir PSA after ADT need a longer follow-up time and more frequent testing of the testosterone and PSA values. It can predict the incidence of CRPC and to ensure that prostate cancer patients receive adequate therapy.

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