Mucous membrane pemphigoid is a rare, systemic autoimmune disease characterized by the production of antigens against adapted antigens on the skin and mucous membranes. This pathology generates a chronic recurrent inflammatory process and aberrant scarring, the diagnosis difficult in the early stages of the disease. Among other characteristics, it can manifest as a chronic and recurrent conjunctivitis, the difficulty and delays the beginning of treatment. The earlier the diagnosis and the beginning of the intervention, the better the patient's visual prognosis. The present work aims to report a case of mucous membrane pemphigoid, describing its main signs and symptoms and its different forms of presentation, facilitating its early diagnosis and correct correction. The ophthalmologist plays a fundamental role in the evolution of the disease, as he is often one of the first doctors to be sought out by these patients.

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Tuberculosis is a systemic disease that can occur with ocular involvement in about 1-2% of cases. The ophthalmopathy clinic is unspecific and difficult to recognize, as the microscopic finding of the pathogen in the lesions is uncommon. In addition, it can lead to irreversible vision loss if not treated early. The present work aims to report a case of ocular involvement of the disease, showing the difficulty of diagnosis and the pharmacological measures adopted at each moment, until the final diagnosis.