Mucous membrane pemphigoid is a rare, systemic autoimmune disease characterized by the production of antigens against adapted antigens on the skin and mucous membranes. This pathology generates a chronic recurrent inflammatory process and aberrant scarring, the diagnosis difficult in the early stages of the disease. Among other characteristics, it can manifest as a chronic and recurrent conjunctivitis, the difficulty and delays the beginning of treatment. The earlier the diagnosis and the beginning of the intervention, the better the patient's visual prognosis. The present work aims to report a case of mucous membrane pemphigoid, describing its main signs and symptoms and its different forms of presentation, facilitating its early diagnosis and correct correction. The ophthalmologist plays a fundamental role in the evolution of the disease, as he is often one of the first doctors to be sought out by these patients.

Introdução: A irrigação arterial do tálamo apresenta diversas variações anatômicas, sendo uma delas a artéria de Percherón (AP). Oclusões dessa artéria originam infartos talâmicos bilaterais simétricos. O trabalho aborda o relato de um caso vivenciado pela equipe de Neurologia de um hospital particular de Belo Horizonte, após um AVC tromboembólico envolvendo a AP. Relato de caso: Paciente A.C.N, 80 anos, masculino, em contexto de estado pró-trombótico devido à neoplasia pancreática, evolui com rebaixamento progressivo do sensório até o coma. À ressonância magnética, as sequências FLAIR evidenciaram aumento da intensidade do sinal em ambos os tálamos, simetricamente. Discussão: A artéria paramediana de Percherón se origina da artéria cerebral posterior (ACP), podendo quatro variantes anatômicas. A variante IIB é chamada artéria de Percherón. Sua oclusão, portanto, justifica infartos talâmicos bilaterais simétricos e ocasiona principalmente rebaixamento do nível de consciência, paralisia do olhar vertical e deterioração da memória. Conclusão: O infarto talâmico bilateral por oclusão da AP gera uma síndrome clínica pouco frequente e de difícil diagnóstico, mas de fundamental conhecimento como diagnóstico diferencial.

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Mucous membrane pemphigoid is a rare, systemic autoimmune disease characterized by the production of antigens against adapted antigens on the skin and mucous membranes. This pathology generates a chronic recurrent inflammatory process and aberrant scarring, the diagnosis difficult in the early stages of the disease. Among other characteristics, it can manifest as a chronic and recurrent conjunctivitis, the difficulty and delays the beginning of treatment. The earlier the diagnosis and the beginning of the intervention, the better the patient's visual prognosis. The present work aims to report a case of mucous membrane pemphigoid, describing its main signs and symptoms and its different forms of presentation, facilitating its early diagnosis and correct correction. The ophthalmologist plays a fundamental role in the evolution of the disease, as he is often one of the first doctors to be sought out by these patients.