This study was carried out to determine the effect of different industrial by-products (pistachio, pomegranate, and olive) as alternative feed sources for sheep. Fifty-two Awassi sheep aged 3 and 4 years were divided into four groups (n=13 per group) concerning age, birth type, milk yield, and lactation period: basal diet without byproducts (CON) and basal diet added with either pistachio shell (PIS), pomegranate hull (POM), or olive pulp (OP). By-products were mixed with the total ration at a rate of 5% and given in the morning and evening feedings. The feeding experiment was continued for 60 days. Milk yield, milk quality, feed consumption, and biochemical parameters such as urea, creatine, triglyceride, total bilirubin, and albumin were determined at 30-day intervals from the beginning of the study. Tukey multiple comparison test was used to compare the research groups. There was no treatment effect on feed consumption. The highest milk yield was measured in sheep fed the POM diet in all periods (the first, second, and third-period means were 1143±111, 967±127, and 785±112 gr, respectively). Milk yield for other groups was similar. At the end of the study, the fat ratio in the CON, PIS, POM, and OP groups were determined to be 6.11±0.30%, 6.25±0.36%, 5.61±0.42%, and 5.97±0.48%, respectively. Protein values were determined as 6.34±0.16%, 6.26%±0.27%, 6.06%±0.23%, and 6.39±0.19% in the same order. There was no statistically significant difference between CON, PIS, POM, and OP groups regarding biochemical parameters. In conclusion, sheep ration can contain PIS, POM, and OP up to 5% as alternative feed sources.