Invasive papillary carcinoma of the breast is a rare form of breast carcinoma. Hereby we report a case of invasive papillary carcinoma of the breast in a 76-year-old otherwise healthy male, who presented at our department with the complaint of left subareolar masses. Mammography demonstrated two masses that were oval and round shaped, sharply demarcated and with micro calcifications on the internal structure. Ultrasonographic (US) analysis revealed solid mass lesions in the left subareolar location. These lesions had cystic areas in the interior structures. Color Doppler US revealed a high resistant vascularization in the central and peripheral parts of the lesions. Pathological examination of the specimen revealed the intracystic component to be invasive papillary carcinoma. In focal areas there was also findings of neuroendocrine differentiation. The patient underwent total mastectomy following an excisional biopsy, as the surgical margin after biopsy was positive for carcinoma. Axillary dissections had negative lymph nodes. After adjuvant chemotherapy and at the 2-year follow-up examination there were no recurrences or metastases. A high index of suspicion is necessary in male patients with solid lesions with cystic components.
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