INTRODUCTION: Gypsophila species have very high medicinal and commercial importance and also contains interesting natural substances. However, there is no report on the essential oil and fatty acid composition of any Gypsophila species. This prompted us to investigate the essential oil and fatty acid composition of Gypsophila laricina Schreb. METHODS: Plant materials were collected during the flowering period. Essential oil composition of aerial parts of Gypsophila laricina Schreb. were analysed by gas chromatography and gas chromatography-mass spectrometry. And the fatty acid compositions were analysed by gas chromatography-mass spectrometry. RESULTS: Sixty-six and ten compounds were identified in the essential oil and fatty acid of G. laricina Schreb. respectively. The major components of the essential oil were hexadecanoic acid (27.03%) and hentriacontane (12.63%). The main compounds of the fatty acid were (Z,Z)-9,12-octadecadienoic acid methyl ester (18: 2) 40.4%, (Z)-9-octadecenoic acid methyl ester (18: 1) 35.0 % and hexadecanoic acid methyl ester (16: 0) 13.0%. DISCUSSION AND CONCLUSION: The result showed that the fatty acid composition are rich in polyunsaturated fatty acids. The essential oils of G. laricina Schreb. were dominated by fatty acid derivatives and n-alkanes. We believe the results obtained u n c o r r e c t e d p r o o f from this research will stimulate further research on the chemistry of Gypsophila species.

Essential oil composition of Gypsophila turcica Hamzaoğlu, Gypsophila pinifolia Boiss. & Hausskn., G. tuberculosa Hub.-Mor., G. eriocalyx Boiss. and G. laricina Schreb. were analyzed by means of gas chromatographymass spectrometry (GC-MS). Thirty six, fourty four, sixty six, forty one and sixty one compounds were identified in the essential oils of G. turcica, G. pinifolia, G. laricina, G. tuberculosa and G. eriocalyx respectively. The major components were determined hentriacontane (12.93 ± 0.4%), 1-octadecanol (8.97 ± 0.1%), hexahydrofarnesyl acetone (6.9 ± 0.09%) and pentacosane (6.63 ± 0.08%) in G. turcica oil, hexadecanoic acid (17.6 ± 0.4%), 1-tetradecanol (7.6 ± 0.1%) and phytol (5.63 ± 0.05%) in G. pinifolia oil, octacosane (6.83%), eicosanal (6.19%), triacontane (6.03%) and heneicosane (5.78%) for G. eriocalyx, hexadecanoic acid (25.3%, 27.0%) and hentriacontane (13.0%, 12.6%) for G. tuberculosa and G. laricina, respectively. Antibacterial activity of G. eriocalyx, G. tuberculosis and G. laricina were investigated against Gram negative (Escherichia coli) and Gram positive (Staphylococcus aureus) bacteria.

Gypsophila türleri, tıbbi ve ticari açıdan çok önemlidirler ve ilginç doğal maddeler içerirler. Bununla birlikte, literatürde Gypsophila türlerinin uçucu yağ ve yağ asidi bileşimi hakkında herhangi bir çalışma bulunmamaktadır. Bu nedenle Gypsophila laricina Schreb.'nin uçucu yağ ve yağ asidi bileşiminin araştırılmasına karar verilmiştir. Gereç ve Yöntemler: Bitki materyali çiçeklenme döneminde toplanılmıştır. G. laricina Schreb. türünün toprak üstü kısmının uçucu yağ bileşimleri gaz kromatografi ve gaz kromatografi-kütle spektrometresi aracılığıyla analiz edilmiştir. Yağ asit bileşimleri gaz kromatografi-kütle spektrometresi aracılığıyla analiz edilmiştir. Bulgular: G. laricina Schreb. uçucu yağlarında altmış altı bileşik ve yağ asitlerinde on bileşik tespit edilmiştir. Uçucu yağın ana bileşenleri heksadekanoik asit (%27.03) ve hentriakontan (%12.63) olarak belirlenmiştir. Yağ asidinin ana bileşenleri ise (Z,Z)-9,12-oktadekadienoik asit metil ester (18:2) %40.4, (Z)-9-octadesenoik asit metil ester (18:1) %35.0 ve heksadekanoik asit metil ester (16:0) %13.0 olarak tespit edilmiştir. Sonuç: Bitki yağ asidi bileşiminin çoklu doymamış yağ asitleri bakımından zengin olduğu saptanmıştır. Bitki uçucu yağının yüksek oranda n-alkan ve yağ aside türevleri içerdiği belirlenmiştir. Bu araştırmadan elde edilen sonuçların, Gypsophila türlerinin kimyası üzerine yapılacak daha ileri araştırmalara katkı sağlayacağı düşünülmektedir. Anahtar kelimeler: Gypsophila laricina, uçucu yağ, yağ asidi Objectives: Gypsophila species have very high medicinal and commercial importance and contain interesting natural substances. However, there is no report on the essential oil or fatty acid composition of any Gypsophila species. This prompted us to investigate the essential oil and fatty acid composition of Gypsophila laricina Schreb. Materials and Methods: Plant materials were collected during the flowering period. The essential oil composition of the aerial parts of G. laricina Schreb. was analyzed by gas chromatography and gas chromatography-mass spectrometry. The fatty acid compositions were analyzed by gas chromatography-mass spectrometry. Results: Sixty-six and ten compounds were identified in the essential oil and fatty acid of G. laricina Schreb., respectively. The major components of the essential oil were hexadecanoic acid (27.03%) and hentriacontane (12.63%). The main compounds of the fatty acid were (Z,Z)-9,12octadecadienoic acid methyl ester (18:2) 40.4%, (Z)-9-octadecenoic acid methyl ester (18:1) 35.0%, and hexadecanoic acid methyl ester (16:0) 13.0%. Conclusion: The results showed that the fatty acid composition is rich in polyunsaturated fatty acids. The essential oils of G. laricina Schreb. were dominated by fatty acid derivatives and n-alkanes. We think the results obtained from this research will stimulate further research on the chemistry of Gypsophila species.

Human genome and phenome data is classified as special categories data under the EU GDPR legislation (Art. 9 GDPR). This requires special care to be taken when processing and reusing this data for research. To enable this in a compliant way, a federated approach was applied to the existing European Genome-phenome Archive ([EGA(https://ega-archive.org/)]) (Freeberg et al., 2022), creating the Federated EGA ([FEGA(https://ega-archive.github.io/ FEGA-onboarding/#what-is-federated-ega)]) (EGA Consortium, n.d.) in 2022. The Nordic countries, Norway, Finland and Sweden, together with Spain and Germany, represent the first federated partners.In the Nordics we have collaborated around our own implementation for our federated EGA nodes. We have done this under the umbrella of the Nordic e-Infrastructure Collaboration (NeIC)[https://neic.no/] (NeIC, n.d.), where we have had three projects over the last 7 years: Tryggve1 (NeIC, 2014-2017), Tryggve2 (NeIC, 2017-2020) and now Heilsa (NeIC, 2021-2024).As we in the nordics now move into production there is a need for both system administrators and helpdesk staff to be able to control and inspect the system. We need to answer questions related to operations, identify errors in order to better manage the services and infrastructure. To standardize this workflow and make the system easier to use, we decided to build a Minimal Viable Product (MVP) for such an “Operator Dashboard” during the ELIXIR Biohackathon 2022.