Background: Meningitis is a serious illness of childhood. CSF Gram stain and culture is the gold standard for diagnosis which is a costly and time consuming. So, this study was conducted with the objective to measure the specificity, sensitivity, positive and negative predictive values and diagnostic accuracy of CSF-CRP in the diagnosis of bacterial meningitis.Methods: This prospective study was conducted in Department of Pediatrics, National Institute of Medical Sciences and Research, Jaipur. Children between 1 month to 12 years of age admitted with acute history of fever and seizure were included. CSF was sent for CRP estimation and other laboratory investigations. CSF CRP was determined qualitatively and value >6mcg/ml was considered positive. Patients were divided into three groups based on clinical and CSF findings. Group 1 (Bacterial meningitis), Group 2 (Aseptic Meningitis) and Group 3 (No meningitis/Control Group). Statistical analysis was done using software SPSS version 23.Results: 120 patients were enrolled in our study. 65% of our cases were males. The mean age of our cases was 74.9±39.8 months. 48 cases had bacterial meningitis, 42 cases had Aseptic Meningitis and 30 cases had no meningitis. CSF-CRP was positive in 35 cases of Bacterial meningitis, 6 cases of aseptic meningitis and negative in all cases of control group. Hence the Sensitivity, Specificity, Positive Predictive Value, Negative Predictive Value and Diagnostic Accuracy of CSF-CRP for diagnosis of bacterial meningitis were 72.92%, 85.71%, 85.71%, 73.47% and 78.89% respectively. CSF-CRP cases of bacterial meningitis were also found to have a poor outcome.Conclusions:CSF-CRP can be used as an initial test for the diagnosis of Bacterial Meningitis till other confirmatory test reports are awaited.
Background: Obesity has acquired an epidemic proportion, leading to increased morbidity and mortality. Early identification and timely intervention in children are the need of the hour. Objective: The objective of the study was to measure and compare the neck circumference (NC) and waist circumference (WC) in normal, overweight, and obese children followed by their correlation with body mass index (BMI). Materials and Methods: This cross-sectional study was conducted in 1000 school-going children of 6–14 years age group. Their BMI, NC, and WC were measured, compared, and correlated by appropriate statistical analysis. Results: The difference between NC and WC of overweight and obese children and that of normal children was statistically significant and the measurements correlated with the BMI. The age-wise cutoff values of NC and WC in male and female children were calculated along with their sensitivity and specificity for detecting obesity. Conclusion: NC and WC are practical, efficient, and cost-effective tools to identify obesity amongst school-going children.
Introduction: Obesity is an emerging epidemic worldwide causing serious public health concern. The upper part of the body as Neck circumference (NC) can be used as a simple and time saving screening tool to evaluate it. Materials and Methods: From January 2018 to June 2019, this school-based prospective observational study was conducted in schools of rural and urban areas near Jaipur taking 1000 children between age group of 6 to14 years. Children with conditions likely to interfere with neck circumference measurement were excluded. All anthropometric measurements were taken with standard techniques, and children were divided as normal, overweight or obese. Results: Out of 1000 subjects, 364 males and 428 females were normal weight, 44 males and 68 females were overweight and 41 males and 19 females were found obese. Intra group comparison of neck circumference in male & females showed significant correlation between normal, overweight & obese children. There was a good positive correlation between BMI and NC for all children. Conclusion: Neck circumference can be used with great reliability to screen overweight and obesity in children.
Introduction: Dengue fever represents a signicant public health problem in tropical and subtropical regions. 70% of total cases are from Asia, especially India. Caused by 4 dengue virus serotypes( DENV-1, DENV-2 DENV-3 and DENV-4), DENV-2 being the most prevalent in India. Incidence and range of cardiac manifestations in dengue fever vary widely. Aims & objectives: To study the incidence and range of cardiac manifestations of dengue fever in children. Material & methods:This is an observational study, conducted in department of pediatrics at National Institute of Medical Sciences & Research, Jaipur in study period of 18 months. A total of 94 patients were included in the study fullling the inclusion criteria. Results: The overall incidence of cardiac manifestations was found to be 31.9%. The incidence of cardiac manifestations in dengue without warning signs was 4.4%, in dengue with warning signs was 52.5% and in severe dengue was 77.7%. Conclusion: Incidence of cardiac manifestations increases with increase in disease severity
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