Momordica balsamina Linn. (Cucurbitaceae), a tendril bearing wild climber has been used as a traditional folk medicine in many countries. It has wide spectrum of medicinal and nutritional values. The fruits of widely available M. balsamina from Southern Haryana were selected for the present study. The phytopharmacological evaluation was performed to prove its medicinal importance.Preliminary phytochemical analysis, quantitative evaluation of phytoconstituents and estimation of antioxidant potential, In vitro antimicrobial activity of various extracts of M. balsamina fruits were determined by using different methods. Preliminary phytochemical screening of fruits showed the presence of fatty acids, carbohydrates, tannins, flavonoids, sterols, saponins and alkaloids The amount of total polyphenols and flavonoids expressed respectively as 201.14 mg/g gallic acid and 103.01 mg/g quercetin in methanol extract of fruits while in the aqueous extract, it was 102.41 mg/g gallic acid and 83.01 mg/g quercetin respectively. The antioxidant potential was studied using different models like DPPH radical scavenging activity, hydrogen peroxide scavenging assay, reducing power assay and phosphomolybate assay. Antimicrobial activity of methanol and aqueous extracts of fruit was determined by
Plant derived compounds have played a vital role in the development of several chemotherapeutic agents. Catharanthus roseus is an important medicinal plant of the apocynaceae family. The leaf extract of Catharanthus roseus have many biological activities such as antibacterial, antioxidant and antidiabetes. The present study was aimed to carry out the phytochemical analysis and the GC-MS analyses of Cathranthus roseus leaf extract ensure activity in the presence bioactive compounds. The leaves designated to the presence of metabolites (proteins, steroids, tannins,glycosides, reducing sugar, carbohydrates,saponins, sterols, terpenoids, acidic compounds, cardiac glycosides, phenols, alkaloids,flavonoids). In the GC the Cathranthus roseus extract result shows the presence of bioactive compounds which revealed a broad spectrum of many medicinal property and antioxidant activity were identified. This study is helped to identify bioactive compound formula and structure which can be used as pharmaceutical industries for drug discovery.
The objective of present study was to perform preliminary phytochemical screening, quantitative estimation of phytoconstituents, and gas chromatography mass spectroscopy studies of Cucumis melo L subsp. Agrestis (Naudin) Pangalo fruit. The petroleum ether, chloroform, alcohol and aqueous extracts of the dried fruits of Cucumis melo L subsp. Agrestis (Naudin) Pangalo were subjected to preliminary phytochemical screening, preliminary phytochemical screening of fruit extracts showed the presence of alkaloids, carbohydrates, glycosides, saponins, sterols, flavonoids, phenolic compounds, tannins, proteins and amino acids Quantitative estimation of alkaloids, carbohydrate, fat contents, saponin, total phenolics content and total flavonoids content in the fruit was done. Further, the hydroalcoholic extract was subjected to gas chromatography-mass spectroscopy (GC-MS) for identification of chemical constituents. GC-MS analysis of hydroalcoholic extract of Cucumis melo L subsp. Agrestis (Naudin) Pangalo fruits revealed the presence of 39 compounds. The results of this study indicates that extracts of Cucumis melo L subsp. Agrestis (Naudin) Pangalo fruits contains various phytoconstituents responsible for its medicinal properties
Inflammation is a physiological host response to external challenges or cellular injury such as pathogens, damaged cells or irritants leading to the release of a complex array of inflammatory mediators and aiding the recovery of tissue structure and function.All inflammatory processes develop along a known sequence: locally increased blood supply, leakage of fluid, small molecule or proteins and infiltration of cells.Inflammation is not a synonym for infection, even in case where inflammation is caused by infection, response includes clinical signs of erythema, edema, hyperalgesia and pain. Since the ancient Greek and Roman era five basic symptoms of inflammation have been known i.e, redness, swelling, heat, pain and deranged function are produced by inflammatory agents such as nitric oxide, prostaglandins, bradykinin, serotonin, leukotrienes and histamine. The inflammatory process is a series of events that can be elicited by numerous stimuli such as infectious and thermal or physical injury through years of ingenious synthesis and structural modifications.
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