A transition metal-and azide-free approach is explored to synthesize 1,4,5-trisubstituted-1,2,3triazoles under sunlight. The reaction proceeds via CÀ N and NÀ N bond formations. These regioselective 1,2,3triazoles are obtained from isatin Schiff bases, benzaldehydes and tosylhydrazine in the presence of base. This protocol offers the structurally diverse 1,2,3-triazole derivatives with 75-90% yields.

A highly efficient regioselective synthesis of 3,4,5-trisubstituted pyrazoles via transition metal-and oxidant-free, three component [3 + 2] cycloaddition with thiazolidinedione chalcones, benzaldehydes and N-tosylhydrazine is described. The reaction proceeds through CÀ C and CÀ N bond formations under mild reaction conditions to produce structurally diverse polysubstituted pyrazoles in moderate to good yields.

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An efficient and eco‐friendly diversity‐oriented synthetic protocol has been presented to synthesize structurally versatile drug‐like molecules under solvent‐free grinding in the presence of Fe(OTs)3/SiO2 as a catalyst. The use of Fe(OTs)3/SiO2 as a recyclable and reusable catalyst has been explored in the synthetic domino protocol involving one‐pot, three component reaction for the synthesis of 4‐pyrrolo‐12‐oxoquinazolines with special features of the protocol like high atom‐economy, operational simplicity, short reaction time and high selectivity with excellent yields.