BackgroundPeriorbital hyperpigmentation (POH) is a very common, yet unexplored aesthetic condition. Topical therapy is mainstay of treatment which includes chemical peels and other depigmenting agents.AimsTo compare clinical efficacy, safety, and tolerability of 20% glycolic acid peels, 15% lactic acid peels, and 12% ferulic acid peels in the treatment of constitutional type of periorbital hyperpigmentation in Indian patients.MethodsNinety patients of constitutional POH were enrolled for 12 weeks. They were divided into three groups of 30 each. In 1st group 20% glycolic acid peeling, in 2nd group 15% lactic acid peeling and in 3rd group 12% ferulic acid peeling sessions were performed at 3 weekly intervals. Clinical improvement was assessed objectively using POH grading, physician's and patient's global assessment, and patient's global tolerance.ResultsSignificant improvement in periorbital hyperpigmentation was noted in all the three groups. Physician and patient's global assessment was excellent with glycolic acid peel followed by ferulic acid peel and lactic acid peel. The incidence of side effects in the form of erythema and itching was maximum with glycolic acid followed by lactic acid and least with ferulic acid, which did not necessitate cessation of therapy.ConclusionGlycolic acid produced the best results among the three peels; however, ferulic acid peel emerged as a safe and effective modality for the treatment of POH.
Lipedematous scalp (LS) is a rare cutaneous disorder of unknown etiology, characterized by significant thickening of subcutaneous tissue which results in a thick, boggy, scalp swelling. To the best of our knowledge, less than 50 cases are reported till date. Hereby, we present a total of four cases of LS, that is, two cases of LS and two cases of unusual associations of LS with alopecia areata and intradermal nevus. LS with intradermal nevus and alopecia areata are the first of its kind, not yet reported till date.So far, only two cases of LS had been reported from Indian population. Hence, our effort is to bring into notice this growing yet an uncommon condition in the Indian population.
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