Penelitian pengaruh model pembelajaran inkuiri terbimbung dari pencapaian kognitif siswa di SMA Negeri 01 Manokwari (studi pada pokok bahasan kelarutan dan hasil kali kelarutan) yang bertujuan untuk mengetahui apakah ada perbedaan yang signifikan antara model pembelajaran inkuiri terbimbing dan model pembelajaran konvensional hasil belajar kognitif siswa dan untuk mengukur persen pengaruh dari kedua model yang digunakan. Penelitian ini menggunakan desain eksperimen metode penelitian kuasi dengan desain pretest posttest. Teknik pengambilan data sampel dilakukan dengan purposive sampling.Instrument yang digunakan untuk mengukur hasil belajar kognitif siswa adalah test essay.Analisis data digunakan adalah analisis deskriptif dan inferensial menggunakan software SPSS 22. Hasil penelitian menunjukkan bahwa ada perbedaan hasil belajar kognitif, model pembelajaran inkuiri terbimbing lebih baik dari model pembelajaran konvensional dengan persen pengaruh 29,49%. Kata Kunci: inkuiri terbimbing, hasil belajar kognitif Abstract. Study the effect of inquiry learning model guided of the cognitive achievement of students in SMA Negeri 01 Manokwari (studies on the subject solubility and solubility product) which aims to determine whether there is a significant difference between the learning model of guided inquiry and conventional learning model of cognitive achievement of students and to measure the percent effect of both models was carried out. This study uses research method quasy experimental design with pretest posttest design. Mechanical sampling was done by purposive sampling. Instrument used to measure cognitive achievement of students is a test essay. Analysis of the data used is descriptive analysis and inferensial using the software SPSS 22. The results showed that there were differences in the results of a cognitive learning which the guided inquiry learning model is better than the conventional learning model with the effect of 29,49 percent.

Antimicrobial-guided fractionation and isolation of the bioactive compounds from the stem bark of Drimys arfakensis Gibbs. were carried out. Two antibacterial compounds were isolated. The sructures of the antibacterial compounds were elucidated by spectroscopic methods such as 1 H NMR, 13 C NMR, 2-D NMR, ESI-MS and EI-MS. Based on the spectroscopic data, the two antibacterial compounds were velutin, 1 and 4-(hydroxyl(oxiran-2-yl)methyl)-2-methoxyphenol, 2. Compound 1 exhibited low activity against methicillin-resistant Staphylococcus aureus (MRSA) (B-1823) with MIC value of 250 g ⋅ mL −1 , while compound 2 possesses strong activity against S. aureus (MRSA) (B-1823) with MIC value of 15.60 g ⋅ mL −1 .No activity of both compounds against Escherichia coli (B-1634) and Candida albicans (B-2219) was observed.

86 Studi adsorpsi limbah organik industri tahu tempe dengan karbon aktif kayu merbau [Intsia bijuga (Colebr) O. Kuntze] Study of adsorption of organic waste from tofu and tempe with activated carbon of merbau wood [Intsia bijuga (Colebr) O. Kuntze] ABSTRACT: Study on adsorption of tofu and tempe industrial organic waste with timber wood [Intsia bijuga (Colebr) O. Kuntze] as the active carbon has been executed. The objective the research is to determine the optimum required consentration of HCl to active the coal of timber wood, discover optimum adsorption capacity of timber charcoal to reduce the level of BOD5 dan COD in fluids waste of tofu and tempe industry. Research method of activating timber wood charcoal is physically by heating 700 o C of temperature and chemically by submersion in HCl 1M, 2M and 3M. First, variation is made of contact duration of timber wood active carbon and fluid waste for 30, 60, 90 and 120 minutes. Then, volume of fluid waste is also differed by 100, 150, 200, 250 and 300 ml per 0.5 gram of active carbon. Result of the research shows that optimum condition for adsorption of tofu and tempe industrial fluid waste are as follow : at consentrate of HCl 3M, contact duration 30 minutes, fluid waste volume 250 ml per 0.5 gram of active carbon, optimum adsorption capacity of timber wood active carbon is achieved which lowering the level of BOD5 and COD of Rizky tofu and tempe industrial fluid waste; each by 60,600 mg/g and 12,500 mg/g. On the state where volume of the waste is 100 ml per 0.5 gram, optimum adsorption capacity of the timber wood active carbon in reducing the BOD5 and COD level of Sukamaju tofu and tempe industrial fluid waste is 82,400 mg/g and 164,200 mg/g each. Keyword : Adsorption, BOD5, COD, tofu and tempe industrial fluid waste, active carbon, wood. ABSTRAK: Studi tentang adsorpsi limbah organik industri tahu dan tempe dengan kayu kayu [Intsia bijuga (Colebr) O. Kuntze] ketika karbon aktif telah dieksekusi. Tujuan dari penelitian ini adalah untuk menentukan konsentrasi HCl yang diperlukan untuk mengaktifkan batubara kayu kayu, menemukan kapasitas adsorpsi arang kayu yang optimal untuk mengurangi tingkat BOD5 dan COD dalam limbah cair industri tahu dan tempe. Metode penelitian untuk mengaktifkan arang kayu kayu secara fisik dengan memanaskan suhu 700oC dan secara kimiawi dengan perendaman dalam HCl 1M, 2M dan 3M. Pertama, variasi dibuat dari durasi kontak karbon aktif kayu dan limbah cair selama 30, 60, 90 dan 120 menit. Kemudian, volume limbah cair juga berbeda dengan 100, 150, 200, 250 dan 300 ml per 0,5 gram karbon aktif. Hasil

Penelitian ini bertujuan untuk menguji aktivitas antibakteri serta mengidentifikasi kandungan metabolit sekunder dari ekstrak metanol buah hitam (H.monticola). Ekstrak buah hitam diperoleh melalui metode ekstraksi maserasi menggunakan pelarut metanol. Hasil skrining fitokimia menunjukkan bahwa ekstrak metanol buah hitam (H.monticola) mengandung tanin dan saponin dengan kadar kategori tinggi. Uji aktivitas antibakteri dilakukan menggunakan metode sumuran dengan kontrol positif kloromfenikol dan kontrol negatif metanol. Hasil uji aktivitas antibakteri terhadap bakteri E.coli menunjukkan aktivitas kuat dengan diameter zona hambat sebesar 11 mm dan bakteri B.subtilis menunjukkan aktivitas sedang dengan zona hambat dengan diameter sebesar 8 mm.

<em>Isolation guided by brine-shrimp ( Artemia salina) bioassay from the stem bark of .Drymis beccariana Gibbs. led to isolate a bioactive compound called Velleral (<strong>1</strong>) ((3aS,8aS)-2,2,8-trimethyl-3,3a.6.8a-tetrahydro-1H-azulene-5,6-dicarbaldehyde).The structure of this compound was elucidated based on physical and spectroscopic data (UV, IR, , ¹H NMR, ¹³C-NMR and&nbsp; GC-MS). This compound showed significant active in the&nbsp; A. salina bioassay with IC₅₀ 2.92 &micro;g/mL and &nbsp;exhibited siginificant cytotoxicity against&nbsp; murine P-388 leukemia cells with IC₅₀ 3,39 &mu;g /mL.Moreover, the compound exhibited antibacterial and antifungal activity especially against&nbsp; Staphyloccocus aureus&nbsp; ATCC 25923 and Candida albians respectively. This result indicates that stem bark of D. beccariana is a potential source of bioactive compounds</em><em>.</em>