Although collaboration assumes a power-sharing arrangement by default, that is, collaborative governance always involves some degree of sharing responsibility for decision making and actions among 745355A RPXXX10.
This article investigates the cognitive linguistic processes involved in organizational identity construction through language-based identity claims. The organizational imaging process constructs an organization's identity in relation to a system of positively and negatively valued conceptual categories. It involves using language to establish a classification scheme and to define the organization within this scheme. The authors develop a framework for identifying these cognitive linguistic processes based on a grounded-theory study of language use in corporate mission statements. Their findings contribute to a deeper understanding of language's role in organizational identity construction.
BackgroundPlatelets play a fundamental role in maintaining hemostasis and have been shown to participate in hematogenous dissemination of tumor cells. Abundant platelets were detected in the tumor microenvironment outside of the blood vessel, thus, platelet -tumor cell interaction outside of the bloodstream may play a role in regulating primary tumor growth and metastasis initiation. However, it is unclear that platelet depletion affects tumor vessel structure and dynamics.MethodsUsing thrombocytopenia induction in two different tumor-bearing mouse models, tumor tissues were performed by Westernblotting and immunohistochemical staining. Vascular permeability was evaluated by determination of intratumoral Evans blue and Miles vascular permeability assay. Furthermore, microdialysis was used to examining the intratumoral extracellular angiogenic growth factors (VEGF, TGF-β) by ELISA.ResultsPlatelet depletion showed no change in tumor growth and reduced lung metastasis. Platelet depletion led to reduced tumor hypoxia and Met receptor activation and was associated with a decreased release of MMP-2, 9, PAI-1, VEGF, and TGF-β. Tumor vessels in platelet-depleted mice showed impaired vessel density and maturation.ConclusionsOur findings demonstrate that platelets within the primary tumor microenvironment play a critical role in the induction of vascular permeability and initiation of tumor metastasis.
Power and trust are two important issues of interorganizational relations in collaborative governance. This article develops a critical conceptual analysis of the dyadic relationship between power and trust in the context of collaborative governance. Three dynamic relationships and seven corresponding propositions are proposed regarding the shared sources of power and trust, the effects of power asymmetry and power sharing on trust building, and the influence of trust building on the management of power relationship in collaborative governance. These dyadic relations will help scholars and practitioners to deal with the dynamics brought forth by power and trust in collaboration.
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