Background: A lot of research have been focused on the area of the arti cial cornea, in our study, a bibliometric analysis was performed on the arti cial cornea to identify the global key research elds and trends over the past 20 years.Methods: Publications about arti cial cornea were retrieved and downloaded from the Web of Science Core Collection (WoSCC) from 2002 to 2021. Citespace and VOSviewer were used to analyze countries, institutions, authors, and related research areas.Results: A total of 829 eligible publications were analyzed. The USA was the most productive country for arti cial cornea, followed by China and Canada. Harvard University was the most proli c institution in this eld. Cornea published most of the studies in this area and Dohlman CH was the most cited author.Conclusions: Bibliometric analysis in our study rstly provides a general perspective on the arti cial cornea, which can be helpful to further explore the issues in the rapidly developing area.

Background: The goal of our study was to construct and validate nomograms for the prognosis of elderly primary ocular adnexal lymphoma (POAL) patients from the Surveillance, Epidemiology, and End Results Program (SEER) database. Methods: We screened the data of POAL patients aged 60 years or older from the SEER database from 2010 to 2015. For the prediction of the cause-special survival (CSS) and the overall survival (OS) at 1, 3, and 5 years in elderly POAL patients, we constructed nomograms. The nomograms were validated by the decision curve analysis (DCA), the area under the curve (AUC), and the calibration curve. Results: Among 821 enrolled POAL patients from the SEER database, 547 were assigned to the training group and 247 to the validation group. The C-index of the two groups was 0.744 and 0.755 in the OS model, 0.745 and 0.855 in the CSS model. The AUC values of the nomograms for OS were 0.819, 0.785, and 0.767 in the training cohorts and 0.872, 0.789, and 0.755in the validation cohorts at 1, 3, and 5 years, respectively. The AUC values of predicted CSS in the training and validation cohorts at 1, 3, and 5 years were 0.754, 0.772, 0.765 and 0.840, 0.864, 0.791, respectively. The calibration and DCA curves also demonstrated the predictive performances. Conclusions: Herein, for predicting the CSS and OS in elderly POAL patients, we constructed predictive nomograms using independent risk factors. These nomograms can help clinicians in predicting the prognosis of elderly POAL patients.

Background: A lot of research have been focused on the area of the artificial cornea, in our study, a bibliometric analysis was performed on the artificial cornea to identify the global key research fields and trends over the past 20 years. Methods: Publications about artificial cornea were retrieved and downloaded from the Web of Science Core Collection (WoSCC) from 2002 to 2021. Citespace and VOSviewer were used to analyze countries, institutions, authors, and related research areas. Results: A total of 829 eligible publications were analyzed. The USA was the most productive country for artificial cornea, followed by China and Canada. Harvard University was the most prolific institution in this field. Cornea published most of the studies in this area and Dohlman CH was the most cited author. Conclusions: Bibliometric analysis in our study firstly provides a general perspective on the artificial cornea, which can be helpful to further explore the issues in the rapidly developing area.