The aim of this study was to extract Eucalyptus oil and Coleus aromaticus oil, and to formulate the lozenge tablets in order to investigate a profitable dosage form. Lozenge tablets were prepared using Roller compression method. The tablets also were evaluated for the physicochemical properties such as hardness, friability, weigh uniformity, thickness and disintegration time. The formulated product showed inhibitory activity against non resistant C.albicans infections thus providing a very good release matrix for the eucalyptus and coleus aromaticus combined extract.The results clearly indicate that the prepared lozenge tablets can be a good alternative for traditional forms.
In the development of buccal drug delivery system, mucoadhesion i.e.; the binding to mucin layer of biological membrane is the key element. Buccal film delivery system consist of at thin film, which is simply placed on the patient's tongue or mucosal tissue, instantly wet by saliva; the film rapidly dissolves, then it rapidly disintegrates and dissolves to release the medication for oral mucosal absorption. Here 5 Formulations of Enalapril Maleate oral films were formulated and produced by using solvent casting technique using the polymer hydroxyl propyl methyl cellulose based on various polymer excipients ratio and were evaluated. The infrared spectra showed stable and compatible character of the drug with the excipients and polymer. The F1 formulation was found to be the best formulation. The Formulation 1 with HPMC 250mg showed optimum swelling properties, maximum drug release and residence time.
Anaemia is a global public health problem affecting 800 million women and children globally. Anaemia is associated with perinatal mortality, child morbidity and mortality, mental development, immune competence, susceptibility to lead poisoning and performance at work. The objective of this article is to identify whether antenatal care‐seeking was associated with the uptake of iron supplementation among pregnant women, adjusting for a range of covariates. This article used data from the cross‐sectional recent Demographic and Health Surveys (DHS) of 12 countries in Asia, Africa and Latin America & the Caribbean regions. The individual‐level data from 273,144 women of reproductive age (15−49 years) were analysed from multi‐country DHS. Multiple Logistic regression analyses were conducted using Predictive Analytics Software for Windows (PASW), Release 18.0. Receiving at least four antenatal care visits was significantly associated with the consumption of 90 or more iron‐containing supplements in 12 low and middle income countries across three regions after adjusting for different household and respondent characteristics, while mass media exposure was found to be a significant predictor in India and Indonesia. Antenatal care seems to be the most important predictor of adherence to iron intake in the selected countries across Africa, Asia, Latin America and Caribbean regions.
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