Green tea is one of the most popular antioxidant drinks in the world. To make green tea, you must first remove the leaves from Camellia sinensis. A form of tea made from unoxidized green leaves from a tea plantation is called green tea. Several other studies have been undertaken over the past year to evaluate whether consuming green tea and extracts has any health benefits. In order to get the health benefits of green tea, the nutrients in the tea must be absorbed. Green tea’s flavonoids and caffeine, which serve to accelerate the elimination of metabolites, contribute to the antioxidant function of green tea. Cancer, heart disease, and aging appear to be the main diseases to be reduced or prevented by these antioxidants. The pharmaceutical and culinary industries can use green tea due to its high potency and lack of adverse effects. Green tea is touted as a natural remedy for a wide range of health issues. Through this, we can better understand the immediate benefits of green tea. Prescription green tea components are discussed along with their antioxidant, anticancer, and antiviral actions in relation to the treatment of cardiovascular diseases (CVD).
Ondansetron tablets that are directly compressed using crospovidone and croscarmellose as a synthetic super disintegrant are the subject of this investigation. A central composite, response surface, randomly quadratic, nonblock (version 13.0.9.0) 32 factorial design is used to optimize the formulation (two-factor three-level). To make things even more complicated, nine different formulation batches (designated as F1–F9) were created. There were three levels of crospovidone and croscarmellose (+1, 0, -1). In addition to that, pre- and postcompressional parameters were evaluated, and all evaluated parameters were found to be within acceptable range. Among all postcompressional parameter dispersion and disintegration time, in vitro drug release experiments (to quantify the amount of medication released from the tablet) and their percentage prediction error were shown to have a significant influence on three dependent variables. Various pre- and postcompression characteristics of each active component were tested in vitro. Bulk density, tap density, angle of repose, Carr’s index, and the Hausner ratio were all included in this analysis, as were many others. This tablet’s hardness and friability were also assessed along with its dimension and weight variations. Additional stability studies may be conducted using the best batch of the product. For this study, we utilised the Design-Expert software to select the formulation F6, which had dispersion times of
17.67
±
0.03
seconds, disintegration times of
120.12
±
0.55
seconds, and percentage drug release measurements of
99.25
±
0.36
within 30 minutes. Predicted values and experimental data had a strong correlation. Fast dissolving pills of ondansetron hydrochloride may be created by compressing the tablets directly.
Leather and goods made out of it are susceptible to microbial growth when it gets suitable temperature and humidity condition as it has a nutrient medium of protein and lipids. In this study, leather samples were collected from the market and stored in 28±2 °C temperature and high humidity to allow microbial growth. The microbes visible on the surface were cultured on the nutrient medium of Potato Dextrose Agar acidified with tartaric acid so that bacterial growth could be inhibited. The distinctive fungi colonies were then subcultured and observed under the microscopic magnifications to identify the fungi genera. Seven visually distinctive fungi colonies were identified as Mucor and Aspergillus genera based on macroscopic appearances and microscopic morphology.
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