We investigated the wound healing efficacy of the Foeniculum vulgare compounds, fenchone and limonene, using an excisional cutaneous wound model in rats. An excision wound was made on the back of the rat and fenchone and limonene were applied topically to the wounds once daily, separately or together, for 10 days. Tissue sections from the wounds were evaluated for histopathology. The healing potential was assessed by comparison to an untreated control group and an olive oil treated sham group. We scored wound healing based on epidermal regeneration, granulation tissue thickness and angiogenesis. After day 6, wound contraction with limonene was significantly better than for the control group. Ten days after treatment, a significant increase was observed in wound contraction and re-epithelialization in both fenchone and limonene oil treated groups compared to the sham group. Groups treated with fenchone and with fenchone + limonene scored significantly higher than the control group, but the difference was not statistically significant compared to the olive oil treated group. Our findings support the beneficial effects of fenchone and limonene for augmenting wound healing. The anti-inflammatory and antimicrobial activities of fenchone and limonene oil increased collagen synthesis and decreased the number of inflammatory cells during wound healing and may be useful for treating skin wounds.

We can conclude that using minced nerve tissue in vein grafts as a conduit increases the regeneration of nerves (almost like the nerve graft group) and it may not be caused by donor-site morbidity. It can be used in the repair of nerve defects instead of autogenous nerve grafts after further experimental evidence and clinical trials.

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PLASTIC SURGERY 2014, Abstract Supplement 164 Figure 1.CONCLUSIONS: Women with larger BMI experience significantly higher rates of mastectomy alone without reconstruction despite having higher satisfaction with reconstruction and similar satisfaction with breast conservation surgery. This supports the notion that all patients being considered for mastectomy should be referred to a plastic surgeon for evaluation and plastic surgeons should highly consider use of abdominal fl ap reconstruction in this population, despite increased risk of complications. BACKGROUND: ADMs in immediate breast reconstruction with breast implants has been well documented and accepted for use. 1 The purpose of this study is to compare the use of porcine ADM with human ADM, made by the same company, in immediate breast reconstruction using breast implants and tissue expanders. Glassberg 2 and Salzberg 3 have reported results that are comparable for use of both products. Glassberg has shown a lower seroma rate with porcine ADM.