Gliosarcoma is a rare primary malignancy of the central nervous system, classified by the World Health Organization as a high-grade glioma and a variant of glioblastoma multiforme. A 57-year-old gentleman presented with a history of left-sided weakness and loss of appetite. Brain MRI was suggestive of right frontal and thalamic mass lesion with contrast enhancement at the periphery. Open biopsy examination revealed a malignant brain tumour presenting a biphasic tissue pattern with gliomatous and mesenchymal components suggestive of gliosarcoma. Although the treatment of gliosarcomas is almost similar to glioblastomas (surgical resection and, depending on clinical status, radiotherapy and/or chemotherapy) the prognosis of gliosarcomas remains poor.

Osteoid osteoma is a benign bone forming tumor of the growing skeleton that is most often seen in young men. It represents by pain and radiologic appearance of a nidus surrounded by osteosclerosis that occurs mostly in long bones of the lower extremity. Occurrence of this tumor in the hand is an uncommon condition. A 35 year old right-hand-dominant man presented to our orthopedic and trauma OPD with an approximately 2 year history of right middle finger pain without any history of trauma. He consulted previously with a local doctor and had undergone xray of the hand with no definitive diagnosis. Computed tomography at our institution was consistent with the diagnosis of osteoid osteoma. The patient was treated with surgical excision of the lesion without bone grafting. The diagnosis of osteoid osteoma was confirmed by histopathology. Follow up visit showed complete resolution of pain. In this case demonstrating that osteoid osteoma is an important differential diagnosis in patients with finger pain.

A primary extra-adrenal retroperitoneal ganglioneuroma was found incidentally in a 22-year-old woman during screening for suspected pregnancy by transvaginal ultrasonography (TVS) and subsequently by magnetic resonance imaging (MRI). TVS and MRI revealed well defined solid mass in retroperitoneal at the level of L5 to S2 vertebrae and displace right common iliac and external iliac vessels. Limited cuts of the region of Computed tomography (CT) were taken and no calcification was identified. Histological examination showed that the lesion was an extra-adrenal retroperitoneal ganglioneuroma composed of mature ganglion cells and subsequently confirmed by immunohistochemistry. Pulse volumel.11 January-December 2018-2019 p.13-18