CHAOS or Congenital High Airway Obstruction Syndrome is a blockage of the fetus's trachea or larynx due to a number of factors including narrowing of the airway, a web-like membrane or even tracheal atresia. In the uterus, the fetal lungs constantly produce fluid and as a result of this airway blockage in the trachea, the lung fluid cannot escape out of the fetal mouth. Because of this the fetus's lungs become distended with fluid and over distended lungs can put pressure on the heart and affect the heart's ability to function. If the heart cannot beat effectively hydrops or congestive heart failure can occur. We present a case of CHAOS with hydrops and associated anomalies, determined prenatally at about 21 weeks by MRI in our hospital.
Gliosarcoma is a rare primary malignancy of the central nervous system, classified by the World Health Organization as a high-grade glioma and a variant of glioblastoma multiforme. A 57-year-old gentleman presented with a history of left-sided weakness and loss of appetite. Brain MRI was suggestive of right frontal and thalamic mass lesion with contrast enhancement at the periphery. Open biopsy examination revealed a malignant brain tumour presenting a biphasic tissue pattern with gliomatous and mesenchymal components suggestive of gliosarcoma. Although the treatment of gliosarcomas is almost similar to glioblastomas (surgical resection and, depending on clinical status, radiotherapy and/or chemotherapy) the prognosis of gliosarcomas remains poor.
Osteoid osteoma is a benign bone forming tumor of the growing skeleton that is most often seen in young men. It represents by pain and radiologic appearance of a nidus surrounded by osteosclerosis that occurs mostly in long bones of the lower extremity. Occurrence of this tumor in the hand is an uncommon condition. A 35 year old right-hand-dominant man presented to our orthopedic and trauma OPD with an approximately 2 year history of right middle finger pain without any history of trauma. He consulted previously with a local doctor and had undergone xray of the hand with no definitive diagnosis. Computed tomography at our institution was consistent with the diagnosis of osteoid osteoma. The patient was treated with surgical excision of the lesion without bone grafting. The diagnosis of osteoid osteoma was confirmed by histopathology. Follow up visit showed complete resolution of pain. In this case demonstrating that osteoid osteoma is an important differential diagnosis in patients with finger pain.
A 57-year-old gentleman presented with a history of leftsided weakness and loss of appetite. Brain MRI was suggestive of right frontal and thalamic mass lesion with contrast enhancement at the periphery. Open biopsy examination revealed a malignant brain tumour presenting a biphasic tissue pattern with gliomatous and mesenchymal components suggestive of gliosarcoma. Although the treatment of gliosarcomas is almost similar to glioblastomas (surgical resection and depending on clinical status, radiotherapy and/or chemotherapy) the prognosis of gliosarcomas remains poor.Medicine Today 2016 Vol.28(1): 46-47
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