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Background To evaluate the efficacy and safety of artificial pneumothorax with position adjustment for computed tomograpy (CT)‐guided percutaneous transthoracic microwave ablation (MWA) of small subpleural lung tumors. Methods Fifty‐six patients with small subpleural lung tumors (< 3.0 cm) entered the study and underwent CT‐guided MWA with (group I: 24 patients with 24 tumors) or without (group II: 32 patients with 34 tumors) the support of artificial pneumothorax. Follow‐up contrast‐enhanced CT scans were reviewed. Pain VAS (visual analog scale) scores at, during, and after ablation were compared between the two groups. Technical success, technique efficacy, local tumor control and complications were compared. Results Creation of the artificial pneumothorax was achieved for 24/24 (100%) in group I and no complication related to the procedure was observed. Technical success of MWA was achieved for all 58 tumors. Primary efficacy of MWA was achieved in 23 of 24 tumors (95.8%) treated in group I, and 32 of 34 tumors (94.1%) treated in group II (P = 0.771). The 12‐month local tumor control was achieved in 87.5% (21/24) in group I compared with 88.2% (30/34) in group II (P = 0.833). Pain VAS scores in group I were significantly decreased after the pneumothorax induction at, during, and after ablation compared with group II (P < 0.05). There was no significant difference in MWA‐related complications (P > 0.05). Conclusion Artificial pneumothorax with position adjustment for CT‐guided MWA is effective and may be safely applied to small subpleural lung tumors. Artificial pneumothorax is a reliable therapy for pain relief.

Background This study prospectively investigated the efficacy and radiation dose of ultralow dose computed tomography (CT)‐guided hook‐wire localization (HWL) at 100 kV with tin filtration (100Sn kV) for small solitary pulmonary nodules. Methods All HWL procedures were performed on a third generation dual‐source CT system. Eighty‐eight consecutive patients undergoing CT‐guided HWL were randomly assigned to standard dose CT (Group A: n = 44; reference 110 kV and 50 mA) or ultralow dose CT (Group B: n =44; 100 Sn kV and 96 mA) protocols. The technical success rate, complications, subjective image quality, and radiation dose were compared between the groups. Results The mean volume CT dose index and total dose‐length product were significantly lower in Group B compared to Group A (0.32 mGy vs. 3.2 ± 1.1 mGy and 12.1 ± 0.97 mGy‐cm vs. 120 ± 40.6 mGy‐cm; P < 0.001). The effective dose in Group B was significantly lower than in Group A (0.17 ± 0.01 mSv vs. 1.68 ± 0.57 mSv, ‐89.8%; P < 0.001). The technical success rates were 100% for both groups. There were no significant differences in complication rates between the protocols ( P > 0.05). The image quality of ultralow dose CT met the requirements for HWL procedure. Conclusion Ultralow dose CT‐guided HWL of solitary pulmonary nodules performed at 100 Sn kVp spectral shaping significantly reduced the radiation dose compared to standard dose CT, with high technical success and acceptable patient safety.

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