Discovery of radioactive X-rays in 1895 by Wilhelm Conrad Roentgen marked the beginning of significant events in diagnostics and treatment of many diseases. The idea of using X-rays in treatment of malignant diseases was born the same year, when X rays were used for treatment of local relapse of breast cancer, upon initiative of medical student Emil Grubbe. This event was followed by important discoveries of radioactive elements. Marie and Pierre Curie discovered polonium and radium and were awarded the Nobel Prize for their discovery in 1903 and 1911. Their daughter, Irène Curie, joined their research on radioactivity and was awarded the Nobel Prize in 1935. The potentials of radiotherapy became increasingly exploited in treatment of oncological patients. The beginning of radiotherapy in Novi Sad dates from 1934 with the arrival of Dr. Nikola Vujić, a specialist in internal medicine and radiology, and when the first universal X-ray generator was installed and used for therapy. After the World War II, radiotherapy was modernized by purchasing modern devices: 4-valve multi-voltage device (Siemens) for deep radiotherapy and contact radiotherapy by Chaoul. Today, radiotherapy for oncological patients in Novi Sad complies with modern trends and protocols (conformal technique). It has the most advanced technical capacities used worldwide and it takes into account the therapeutical effects and patients' quality of life

Following the shift in therapy of tuberculosis in the mid-19th century, by the beginning of the 20th century numerous tuberculosis sanatoria were established in Western Europe. Being an institutional novelty in the medical practice, sanatoria spread within the first 20 years of the 20th century to Central and Eastern Europe, including the southern region of the Panonian plain, the present-day Province of Vojvodina in Serbia north of the rivers Sava and Danube. The health policy and regulations of the newly built state - the Kingdom of Serbs, Croats and Slovenians/Yugoslavia, provided a rather liberal framework for introducing the concept of sanatorium. Soon after the World War I there were 14 sanatoria in this region, and the period of their expansion was between 1920 and 1939 when at least 27 sanatoria were founded, more than half of the total number of 46 sanatoria in the whole state in that period. However, only two of these were for pulmonary diseases. One of them was privately owned the open public sanatorium the English-Yugoslav Hospital for Paediatric Osteo-Articular Tuberculosis in Sremska Kamenica, and the other was state-run (at Iriški venac, on the Fruška Gora mountain, as a unit of the Department for Lung Disease of the Main Regional Hospital). All the others were actually small private specialized hospitals in 6 towns (Novi Sad, Subotica, Sombor, Vrbas, Vršac, Pančevo,) providing medical treatment of well-off, mostly gynaecological and surgical patients. The majority of sanatoria founded in the period 1920-1939 were in or close to the city of Novi Sad, the administrative headquarters of the province (the Danube Banovina at that time) with a growing population. A total of 10 sanatoria were open in the city of Novi Sad, with cumulative bed capacity varying from 60 to 130. None of these worked in newly built buildings, but in private houses adapted for medical purpose in accordance with legal requirements. The decline of sanatoria in Vojvodina began with the very outbreak of the World War II and they never regained their social role. Soon after the Hungarian fascist occupation the majority of owners/ founders were terrorized and forced to close their sanatoria, some of them to leave country and some were even killed or deported to concentration camps

The house in Gajeva Street is now used as the municipality office. However, this house with its story recommends itself to become a house for a special social function, such as a museum of medical history of Novi Sad. A small investment could make it possible to collect, preserve and display the valuable records of our past, which is something we do owe to the generations to come.

The first publication about surgical treatment of tumors in children in medical literature dates from the beginning of the 19th century. Operations were a method of choice to treat. New development in science such as microscopy research, anesthesia, antisepsis, X-ray, and radium therapy has changed the approach to malignant diseases. The remarkable achievements in survival of oncology patients today are the results of a multimodal, multi-institutional, and multidisciplinary collaboration. Pediatric oncology differs from the oncology for adult patients in the type, generic considerations, diagnostics, and treatment approach. Many pediatric subspecialties are required to evaluate, treat, and manage children with malignant diseases, including provision of primary modalities and multiple supportive care services

The aim of the study was to check the results of the protocol with neoadjuvant chemoirradiation for the treatment of locally advanced rectal cancer. The value of preoperative methods for staging of rectal cancer was also studied. In the period 1st of June 2000 - 31st of December 2005, 116 patients were included into the study, all with histologically proven rectal cancer up to 12 cm from anal verge and all with T3/T4 No-2 M0 stage. Median follow up was 48 months. Operability rate was 90,1%, local recurrency 12%, and survival 78%, though only 66% without sign of local or distant recurrency.