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The paper describes methodology for quantification of fuel cladding failure as a result of Loss of Coolant Accident. The methodology is based on external coupling of the RELAP5 code and TRANSURANUS code. The thermo-hydraulic response of the unit to the accident is simulated by RELAP5 code, providing initial and boundary conditions for the thermo-mechanical simulation by the TRANSURANUS code. Cladding failure criterion of the TRANSURANUS code, derived and implemented into the code in the framework of EXTRA EURATOM 5th Framework Programme is used. Cladding failure probability is evaluated by the Monte Carlo algorithm varying the outer cladding temperature. In the second part of the paper, an example of application of the methodology for typical maximum design basis accident of the VVER-440 is given, presenting every step of methodology and typical failure rate for this type of accident.

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