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We have concluded that parts of the brain with an important role for the survival have a strong expression of c-fos gene.

Introduction. Deep brain stimulation is a stereotactic neurosurgical method used in the treatment of Parkinson?s disease and some other movement disorders. The application of deep brain stimulation in the treatment of certain psychiatric disorders has been intensively investigated taking into account the current knowledge of neurobiological basis of mood regulation, cognition, and behaviour. This paper has been aimed at presenting the available data on experience in the application of deep brain stimulation in the treatment of psychiatric disorders. It gives an overview of scientific and professional literature, bearing in mind all the contemporary approaches in the treatment of certain psychiatric disorders. Research results available so far in the treatment of treatment-resistant depression, obsessive-compulsive disorder, Gilles de la Tourette syndrome, addiction and Alzheimer?s dementia, are affirmative concerning the efficacy of the method and low risk of adverse effects. Deep brain stimulation, as a relatively new neurosurgical method in the treatment of psychiatric disorders, is being intensively developed, and it is certainly going to be one of the treatments of choice, primarily of treatment-resistant disorders.

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ABS TRACT:Idiopathic thrombocytopenia side-effect of lithium in a patient with schizophrenia There are numerous data on the effects of lithium on the hematopoietic system, especially in aplastic anemia and thrombocytopenia. This case shows a dual effect of therapy with lithium carbonate in a 49-year-old patient with schizophrenic psychosis and idiopathic thrombocytopenia. Lithium was introduced as a therapy firstly in order to augment the existing antipsychotic therapy, and secondly as potential protection against hematopoiesis in order to increase the number of thrombocytes after idiopathic thrombocytopenia had been diagnosed.