Objective: to analyze the risk of suicide in medical students with Major Depressive Episode. Methods: A quantitative study was carried out with medical students at the University Center of Patos -UNIFIP, from June to August 2021. The Mini 5.0.0 tool (Mini International Neuropsychiatric Interview), adapted for the virtual environment, was used. A form was built using Google Forms, sent through social networks (Instagram, WhatsApp, Facebook and Telegram). Analyzes were performed using the Statistical Package for the Social Sciences (SPSS V21) statistical program.Results: The sample included the participation of 99 university students (99/527, corresponding to 0.18% of the total sample). Of these, 61.6% are female students and 38.4% are male. Ages ranged between 19 and 43 years. Among the individuals presented, 1/3 have a Current Major Depressive Episode (EDMA) (n=33), which is the main psychiatric comorbidity associated with GAD. The prevalence of EDMA in women (41%) was higher among men (21.1%). Regarding the risk of suicide, it was observed in 19.6% of patients with Major Depressive Episode (EDM), who say bad thoughts such as doing something harm to themselves. Conclusion: The prevalence of suicide risk and the presence of major depressive disorder were observed in association with depressive episodes. Furthermore, the fact that an individual has more than one disorder, such as a mood disorder, and greater severity of symptoms are factors associated with a higher proportion of suicide risk. Finally, it was noted that there is a higher prevalence of diagnosis in women when compared to men.