Purpose-To evaluate the efficacy of repeat 360° selective laser trabeculoplasty (SLT) in glaucoma patients with prior successful 360° SLT. Design-Retrospective chart reviewMethods-Forty-four eyes of 35 patients, ≥ 18 years of age, with open-angle glaucoma (primary open-angle, pseudoexfoliation or pigmentary glaucoma), uncontrolled on maximum tolerable medical therapy, underwent an initial 360° SLT (SLT1), which was successful for ≥ 6 months, but eventually lost efficacy and was followed by a repeat 360° SLT (SLT2). Patients with prior argon laser trabeculoplasty or other glaucoma surgery, before or during the study period, were excluded. Intraocular pressure (IOP) measurements were recorded before each procedure and 1-4 weeks, 1-3 months, and 5-8 months post-treatment, as well 15-21 weeks after the initial SLT.Results-Reduction in IOP after SLT1 and SLT2 was significantly less with repeat treatment at 1-3 months, with average decreases of −5.0 and −2.9mmHg, respectively (p=.01); but there were no statistically significant differences between treatments at the other equivalent time points. Using a definition of "success" as ≥ 20% peak IOP reduction, success rates for SLT1 and SLT2 were not significantly different. There was also no significant difference in eyes that received SLT2 6-12 months after SLT1 compared to those that received SLT2 12 months or more after SLT1.Conclusions-Our findings suggest that repeat 360° SLT may be safe and effective after an initially successful 360° SLT has failed. These results may be achieved as early as six months after the first treatment.

The heat of fusion of solid parahydrogen has been measured for the first time at pressures above that of the triple point. The measurements were carried out up to a pressure of 338 atm. The heat of fusion was found to be a linear function of the pressure, and its values are well reproduced by the equation ΔHf = 0.04415 P+28.04, in which ΔHf is the heat of fusion in calories per gram mole and P the pressure in atmospheres. The value given by this equation for the triple point of hydrogen is 28.04, which compares with literature values of 28.03, 28.08, and 28.3 cal/mole. A few independent measurements were also made of temperatures corresponding to various pressures along the melting line for parahydrogen; most of the measured temperatures agree within 0.1°K of those previously reported in the literature.

591liydrutropic salts such as sodiuin benzoate or sodium xylene sulfonate, sodium iodide was relatively ineffective as a solulilizing agent, giving only a 10% increase in acrylonitrile solubility even in the absence of alkalies. These workers observed that at higher alkali concentrations, the acrylonitrile was &dquo;salted out&dquo; hy the sodium iodide-sodium hydroxide mixture more readily than if no sodium iodide were present. > Their solubility measurements were made at 25°C, while the cyanoethylation was conducted at 60°C. It is, of course, possible that at the higher temperature, sodium iodide would show appreciable hy-drotrol>ic action for acrylonitrile in the 2.3% sodium hydroxide used for cyanoethylation. Evidence on this question is still lacking.'Vhether alkali iodides exert appreciable soluhilizing effects on benzyl chloride is unknown. At the high concentrations of alkali ( 18-23% ) used in benzylation, the existing evidence suggests hydrotropic effects would not contribute significantly to the observed catalysis, though they might offset salting-out effects which would otherwise prevent the catalysis from occurring. _ ' ' Acknowledgment The authors wish to express their appreciation to members of Textile Testing Investigations for the breaking strength determinations included in this report.

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