Objective: to analyze the clinical history and evolution of children and adolescents with IH, emphasizing some of their peculiar features.Methods: we followed 471 patients with IH at an outpatient clinic. Patients were submitted to the following protocol: abdominal X-ray, kidney and urinary tract ultrasonography; urinary ionogram, blood gas and biochemical analyses; 24-hour urine for measurement of calcium and other electrolytes and creatinine; urinalysis, urine culture and phase-contrast microscopy; second morning urine collected after fasting for measurement of calcium and creatinine.Results: at the time of diagnosis, 6% of the patients were infants, 15% pre-school children, 55% school children, and 24% adolescents; 56% of them were boys. Clinical and laboratory findings were: 47% had hematuria and abdominal pain, 31% had isolated hematuria, 14% isolated abdominal pain, and 8% had urinary tract infection, nocturnal enuresis, suprapubic pain or urethralgia, or the frequency/urgency syndrome with urinary incontinence. Hypercalciuria was associated with urolithiasis in 56% of patients. There was association with hyperuricosuria in 18.5% of the cases, and hypocitraturia in 8.5% of the cases. Evolution was poor for 33% of the patients, with recurrence of nephrolithiasis, persistence of hematuria, and abdominal pain.Conclusions: IH must be diagnosed and treated with criteria in order to reduce consequences such as hematuria, abdominal pain, urinary stone formation and possible bone involvement. Signs and symptoms such as urgency and urinary incontinence, suprapubic pain and nocturnal enuresis may result from renal hyperexcretion of calcium.J Pediatr (Rio J) 2001; 77 (2): 101-4: hematuria, enuresis, urinary incontinence. ResumoObjetivo: analisar a história clínica e evolução de crianças e adolescentes com HI, ressaltando peculiaridades próprias destes pacientes.Métodos: 471 pacientes portadores de HI têm sido acompanhados em regime ambulatorial, sendo submetidos ao protocolo: Rx de abdome, ultra-sonografia de rins e vias urinárias; ionograma, gasometria e bioquímica de sangue; urina de 24 horas para dosagem de cálcio e outros eletrólitos e creatinina; urinálise, urocultura e microscopia de contraste de fase; urina de segunda micção matinal em jejum para dosagem de cálcio e creatinina.Resultados: 56% masculinos e 44% femininos; 56% brancos, 37% não-brancos e 7% sem relato da cor da pele. Ao diagnóstico 6% eram lactentes, 15% pré-escolares, 55% escolares e 24% adolescentes. 47% tinha hematúria associada à dor abdominal, 31% hematúria isolada, 14% dor abdominal isolada, e 8% tinham infecção urinária, enurese noturna, dor suprapúbica ou uretral ou a síndrome miccional com freqüência/urgência e incontinência urinária. A associação de hipercalciúria com litíase do trato urinário foi positiva em 56% dos pacientes. Em 18,5% houve associação com hiperuricosúria e em 8,5% com hipocitratúria. 33% dos pacientes tiveram má evolução com recorrência de nefrolitíase, persistência de hematúria e dor abdominal.Conclusões: a HI...
Objective: to analyze the clinical history and evolution of children and adolescents with IH, emphasizing some of their peculiar features.Methods: we followed 471 patients with IH at an outpatient clinic. Patients were submitted to the following protocol: abdominal X-ray, kidney and urinary tract ultrasonography; urinary ionogram, blood gas and biochemical analyses; 24-hour urine for measurement of calcium and other electrolytes and creatinine; urinalysis, urine culture and phase-contrast microscopy; second morning urine collected after fasting for measurement of calcium and creatinine.Results: at the time of diagnosis, 6% of the patients were infants, 15% pre-school children, 55% school children, and 24% adolescents; 56% of them were boys. Clinical and laboratory findings were: 47% had hematuria and abdominal pain, 31% had isolated hematuria, 14% isolated abdominal pain, and 8% had urinary tract infection, nocturnal enuresis, suprapubic pain or urethralgia, or the frequency/urgency syndrome with urinary incontinence. Hypercalciuria was associated with urolithiasis in 56% of patients. There was association with hyperuricosuria in 18.5% of the cases, and hypocitraturia in 8.5% of the cases. Evolution was poor for 33% of the patients, with recurrence of nephrolithiasis, persistence of hematuria, and abdominal pain.Conclusions: IH must be diagnosed and treated with criteria in order to reduce consequences such as hematuria, abdominal pain, urinary stone formation and possible bone involvement. Signs and symptoms such as urgency and urinary incontinence, suprapubic pain and nocturnal enuresis may result from renal hyperexcretion of calcium.J Pediatr (Rio J) 2001; 77 (2): 101-4: hematuria, enuresis, urinary incontinence. ResumoObjetivo: analisar a história clínica e evolução de crianças e adolescentes com HI, ressaltando peculiaridades próprias destes pacientes.Métodos: 471 pacientes portadores de HI têm sido acompanhados em regime ambulatorial, sendo submetidos ao protocolo: Rx de abdome, ultra-sonografia de rins e vias urinárias; ionograma, gasometria e bioquímica de sangue; urina de 24 horas para dosagem de cálcio e outros eletrólitos e creatinina; urinálise, urocultura e microscopia de contraste de fase; urina de segunda micção matinal em jejum para dosagem de cálcio e creatinina.Resultados: 56% masculinos e 44% femininos; 56% brancos, 37% não-brancos e 7% sem relato da cor da pele. Ao diagnóstico 6% eram lactentes, 15% pré-escolares, 55% escolares e 24% adolescentes. 47% tinha hematúria associada à dor abdominal, 31% hematúria isolada, 14% dor abdominal isolada, e 8% tinham infecção urinária, enurese noturna, dor suprapúbica ou uretral ou a síndrome miccional com freqüência/urgência e incontinência urinária. A associação de hipercalciúria com litíase do trato urinário foi positiva em 56% dos pacientes. Em 18,5% houve associação com hiperuricosúria e em 8,5% com hipocitratúria. 33% dos pacientes tiveram má evolução com recorrência de nefrolitíase, persistência de hematúria e dor abdominal.Conclusões: a HI...
RESUMO:Objetivou-se avaliar a dinâmica ovariana e a taxa de concepção de fêmeas Nelore submetidas à IATF utilizando o benzoato ou o cipionato de estradiol como indutores da ovulação e inseminadas nos turnos da manhã ou da tarde. Para tanto, 296 animais receberam um dispositivo intravaginal de progesterona e a aplicação de 2,0 mg benzoato de estradiol em um dia aleatório, denominado D0. No D8 houve a remoção dos implantes, a administração de 500 µg de Cloprostenol e 300 UI de gonodotrofina coriônica equina. Neste momento, metade dos animais recebeu 1,0 mg de cipionato de estradiol, e a outra metade 1,0 mg de benzoato de estradiol no dia posterior (D9), constituindo os tratamentos CE e BE, respectivamente. No experimento 1, 38 animais (19 de cada tratamento) tiveram a dinâmica ovariana acompanhada por ultrassonografia. No experimento 2, 258 animais distribuídos nos tratamentos (CE e BE) foram estratificados para que as inseminações ocorressem pelo turno da manhã (M) ou da tarde (T) do D10, constituindo os grupos CE-M (n = 65), BE-M (n = 65), CE-T (n = 63) e BE-T (n = 65). Não foi encontrada diferença entre os tratamentos para as variáveis: diâmetro do folículo ovulatório, momento das ovulações, taxa de ovulação e diâmetro do corpo lúteo, entretanto, os animais do grupo CE apresentaram maior taxa de crescimento folicular (CE: 0,48 mm/dia; BE: 0,29 mm/dia). Não houve diferença na taxa de concepção entre os grupos CE-M (52,3%), BE-M (41,5%), CE-T (41,3%) e BE-T (49,2%). O emprego do cipionato em substituição ao benzoato proporciona uma redução no número de manejos sem comprometer a dinâmica ovariana e os índices de concepção. Adicionalmente, a extensão no intervalo para realização das inseminações revela-se como uma alternativa aos modelos de gestão no uso desta biotecnologia. Palavras-chave: corpo lúteo; dinâmica folicular; IATF; ultrassonografia EFFICIENCY OF ESTRADIOL CYPIONATE AND ESTRADIOL BENZOATE IN OVULATION INDUCER PROTOCOLS ON OVARIAN DYNAMICS AND CONCEPTION RATE OF NELORE FEMALES INSEMINATED AT DIFFERENT TIMES ABSTRACT:We aim to evaluate the ovarian dynamics and conception rates of Nelore females subjected to TAI using benzoate or estradiol cypionate as ovulation inducers and inseminated that morning or afternoon. For this, 296 animals received an intravaginal progesterone device and 2,0 mg of estradiol benzoate applied on a random stage of the oestrous cycle, named D0. On D8, the devices were removed and 500 µg of Cloprostenol and 300 IU of equine chorionic gonadotropin were administered. At that time, half of the animals received 1,0 mg of estradiol cypionate, and the other half received 1,0 mg of estradiol benzoate on the following day (D9), establishing the EC and EB treatments respectively. On experiment 1, 38 animals (19 for each treatment) had the ovarian dynamics accompanied by ultrasonography. On experiment 2, 258 animals were randomly distributed according to treatments (EC and EB) in order for the inseminations to occur in the morning (M) or in the afternoon (T) of D10, establishing thus groups ...
Resumo -O objetivo deste trabalho foi determinar o efeito do número de folículos antrais sobre as taxas de concepção de fêmeas Nelore, em programa de inseminação artificial em tempo fixo (IATF). Para isso, 481 fêmeas foram submetidas a um protocolo de IATF e avaliadas quanto à contagem de folículos antrais (CFA) e ao diagnóstico de gestação. Os animais foram agrupados nas categorias de CFA baixa (<34 folículos), intermediária (34-53) e alta (>53). Não houve diferença entre as taxas de concepção obtidas nas categorias de CFA em IATF com uso de gonadotrofina coriônica.Termos para indexação: Bos taurus indicus, população folicular antral, taxa de concepção. Fertility of Nellore females after a fixed-time artificial insemination according to antral follicle countAbstract -The objective of this work was to determine the effect of antral follicle number (AFC) on the conception rates of Nellore females, in a fixed-time artificial insemination (FTAI) program. For that, 481 females were subjected to a FTAI protocol and evaluated for antral follicle counts (AFC) and pregnancy diagnosis. The animals were grouped into the AFC categories considered as low (<34 follicles), intermediate (34-53) and high (>53). There was no difference between the conception rates obtained for the AFC categories in FTAI protocol with use of chorionic gonatropin.
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