This study shows the protective effect of AI on NaF-induced hypertension and genotoxicity through antioxidant and ERK 1/2 signaling in rats.

No abstract

Ulcerative lymphangitis, a bacterial infection primarily caused byCorynebacterium pseudotuberculosis is an important infectious disease of horses and ruminants affecting the cutaneous lymphatic vessels. Differential diagnosis of ulcerative lymphangitis include epizootic lymphangitis, a fungal infection, sporotrichosis caused by Sporothrix schenckii, pyoderma, and glanders. The aim of this study is to describe the successful management protocol of ulcerative lymphangitis in a stallion in Ibadan, Nigeria. A 12 year old Arewa stallion was presented in December 2019 with cutaneous lesions, ulcerated wounds, anorexia, and weight loss. The lesions were present around the limbs, chest, facial and abdominal regions. Based on case history, the client previously had a mare presenting similar conditions, and decided to manage the mare according to his knowledge. Due to the unresponsiveness of the mare to the protocol incorporated by the client, resulted in the death of the mare. Furthermore, the client reported that three months earlier, the stallion had previously been managed for cutaneous myiasis with forceful expulsion of worms from the skin and the administration of ivermectin. Based on clinical and laboratory examinations, the case was diagnosed as ulcerative lymphangitis. Therapeutic management protocol includes the use of levofloxacin, an antibiotic of the fluoroquinolone drug class, diclofenac, tetanus antitoxin, and supportive therapy. The management protocol proved successful, with the stallion recovering 3 weeks posttreatment.

Equine enteroliths are mineral accumulations of magnesium-ammonium-phosphate (struvite) around a foreign object that form round, triangular, or flat stones inside the bowel usually over the course of multiple years. They form in the large colon of horses where they can remain for some time until they move and cause an obstruction in the large or small colon, resulting in colic. A 15year old Dongola stallion was presented with a bout of colic, history revealed that the horse repeatedly had been having recurrent bouts of colic. The animal was not responding to treatment rather it was getting worse. The horse died before surgical intervention could be carried out. At post mortem twenty enteroliths were discovered in the colon.