Objective: Prealbumin renamed transthyretin is a protein that is made in the liver and released in the blood and has been used as a beneficial nutritional indicator for long years. It aimed to investigate whether serum prealbumin level is a marker of mortality in patients hospitalized in the intensive care unit. Methods: This retrospective and single-center study was carried out at level 3 intensive care unit. Data were collected from hospital electronic records and patient file archives. Patient age, gender, acute physiologic and chronic health evaluation score, nutritional risk screening 2002, nutric score, neutr ophil -lymp hocyt e ratio, need for mechanical ventilation and duration, intensive care unit length of stay, comorbid conditions, the situation of nutrition support, causes of enteral feeding intolerance, the situation of protein and energy intake (7 days), laboratory parameters (included prealbumin (0 and 7 days)) at the time of admission to intensive care unit, and mortality status were recorded. Patients were divided into 2 groups as survivors and non-survivors, and the differences between the 2 groups were analyzed for all parameters. Results: Sixty-three (60%) were female of 105 patients who participated in this study. The mean age was 59 ± 23 years. The mortality rate was 48.6%. The length of stay in the intensive care unit was 30 ± 34 days. The median level of serum albumin (g/dL) on day 1 was 2.7 (2.3-3.2) and on day 7, it was 2.5 (2.1-2.8). The mean level of serum prealbumin (mg/dL) on day 1 was 13.8 ± 6.6 and on day 7, it was 12.5 ± 6.5. Prealbumin (on days 0 and 7) values were not different between survivors and non-survivors (for all P < .05). In the binary logistic regression analysis, age and albumin value (on day 7) were found to be independent risk factors for mortality (odds ratio: 1.038 (1.002-1.075), P = .036, odds ratio: 1.148 (1.021-1.290), P = .021), respectively. Conclusions: Prealbumin levels did not differ for critically ill patients with and without mortality.

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Objective: Modified Nutrition Risk in Critically Patients is a classification scale that has been widely used all over the world recently to determine the level and degree of nutritional risk in individuals treated in intensive care units. It was analyzed whether the length of stay in the intensive care units as different in individuals classified according to the Modified Nutrition Risk in Critically score level. Methods: In this retrospective study, which included 100 patients, the age and gender of the patients, the laboratory parameters at the time of first admission to the intensive care units, the prognostic indicators including the Acute Physiologic and Chronic Health Evaluation Score II, Sequential Organ Failure Assessment, and Modified Nutrition Risk in Critically scores calculated in the first day, the need for invasive mechanical ventilation, and if ventilated duration of invasive mechanical ventilation, intensive care units length of stay, comorbid conditions, and death rate were recorded. Results: Sixty (60%) patients were male. The median age was 66 (48-79) years. The patients with high Modified Nutrition Risk in Critically score were 26 (26%). Intensive care units length of stay was 19 (10-38) days. Acute Physiologic and Chronic Health Evaluation II score was 18 (11-24). Mortality rate was 39%. High Modified Nutrition Risk in Critically score group had higher Acute Physiologic and Chronic Health Evaluation II score, the necessity of invasive mechanical ventilation, length of stay in the critical care unit, and death rate as compared to low Modified Nutrition Risk in Critically score group (for all P > .05) and need of invasive mechanical ventilation and Modified Nutrition Risk in Critically score ≥ 5 were shown to have a remarkable influence on length of stay in the critical care unit. Conclusion: The need for invasive mechanical ventilation and Modified Nutrition Risk in Critically score ≥ 5 were shown to have remarkable influence on intensive care units length of stay.

Akut pankreatit (AP), karın ağrısı ve amilaz ve lipaz yüksekliğinin olduğu, mortalite ve morbiditesi yüksek bir hastalıktır. Bu çalışmada; hastanemizde AP tanısı ile yatırılan hastaların demografik verileri, klinik ve laboratuar bulguları incelenerek, prognoz üzerine etkileri retrospektif olarak araştırıldı. Araçlar ve Yöntem: Çalışmamız Ocak 2016-Ocak 2019 tarihleri arasında hastanemiz Dahiliye ve Acil Tıp kliniğinde AP tanısı ile takip edilen 457 hasta üzerinde yapıldı. Bulgular: Hastaların 160'ı erkek(%35), 297'si kadın (%65) ve yaş ortalaması 57.7 (min:18-max:106) idi. Hastalarımızdan 6'sı (%1.4)'sı ex olmuştu. Ex olan hastlarımızın tamamı 70 yaş üstü ve en az bir komorbiditesi mevcuttu. Hafif ve şiddetli AP hastaları arasında cinsiyet, etiyoloji, CRP, amilaz ve yatış gün sayısı açısından istatistiki olarak anlamlı fark yokken, yaş açısından ise kuvvetli anlamlılık vardı. Hastalarımızın 369(%80.7)'unun etiyolojisi biliyer olup, 88(%19.3)'inde ise nonbiliyer nedenler idi. Tüm hastaların Ranson ortalaması 1.28 idi Sonuç: Hastalığın şiddetinin yaş ile belirgin arttığı göz önüne alındığında özellikle yaşlı hastaların takibinin dikkatle yapılması ve yoğun bakım üniteleri olan merkezde takip edilmesinin önemli olduğunu düşünmekteyiz. AP klinik özelliklerinin farklı olması ve değişkenlik göstermesi nedeniyle klinik şiddetin erken dönemde belirlenmesi etkin tedavi yaklaşımı ve gelişebilecek komplikasyonların minimuma indirilmesini sağlayabilir.

No abstract