HIF-1 alpha and HMOX-1 provided protection against H(2)O(2)-induced damage in HL-1 cells. Remote gene delivery of HIF-1 alpha afforded cardioprotective effects. These were dependent on HMOX activity, as an HMOX blocker abolished the effects, and they were mimicked by pre-treatment with HMOX-1. Downstream to HMOX-1, bilirubin as well as carbon monoxide may be organ effectors.

No abstract

The aim of this study is to address the association between Muslim religiosity and health outcomes, and investigate if religious Muslims are more likely to be of disadvantage of health than non-religious Muslims. A cross-sectional study-design is used with a representative sample of Muslims in Norway including 2661 respondents in age 16 years–74 years from the “The Survey On Living Conditions Among Persons With An Immigrant Background 2016”, conducted by Statistics Norway. Multivariate logistic regression analyses were conducted to investigate the relationship between Muslim religiosity and health outcomes. The health outcomes in focus are self-reported health, diabetes, cardiovascular diseases, neck and back illnesses, mental health problems, sleeping disorders, consumption of alcohol, and smoking. Association between Muslim religiosity and positive health outcomes were found. Smoking and alcohol consumption were negatively associated with Muslim religiosity. The findings suggest no evidence that religious Muslims are more likely than non-religious Muslims to be of disadvantage of health, and the study do not support the premise that Islam as a barrier to health. In addition, our findings suggest that Muslim religiosity might serve as a resource either predicting better health outcomes or that Muslim religiosity may be a factor that exists if good health is evident. As our findings cannot define any cause-effect relation between Muslim religiosity and health outcomes, given the cross-sectional design of the study, we emphasize the need of further research that investigates how Muslim religiosity is associated to health.

Tuberculosis (TB) is a communicable systemic infectious disease with high morbidity and mortality associated with it. Resistance to medications used to treat tuberculosis has been on the rise in recent years. (multidrug-resistant tuberculosis)  (MDR-TB)  is a significant challenge to (TB) control around the world. An observational research was conducted in a tertiary care teaching hospital to determine the interim pharmacological and microbial results of Rifampicin resistance TB patients. Data from Santhiram Medical College and General Hospital, Nandyal, Kurnool Dist. Andhra Pradesh were obtained from Aug 2020 to Feb 2021, after receiving ethical approval from the Institutional Ethics Committee. The effects of the regimen are determined in terms of cure, finished treatment, treatment failure, number of patients moved to MDR-TB, number of patients who died in long-term MDR-TB regimen patients. Microsoft Excel 2007 was used to analyse the data. There were 82 male and 23 female out of 105 patients included in the study. Of these 75 patients were from rural areas and 40 from urban areas Using the Chi-square test and X2=12.1026, p=0.0005, which was important, the correlation between geographical spread and treatment result was determined. Out of 115 patients, 99 (86.09 percent) were cured of their disease, 06 (5.22 percent) died, 10 (8.69 percent) developed MDR-TB, and 2 (1.74 percent) were deemed medication errors. Males between the ages of 51 and 70 are more vulnerable to TB than females, according to our results. Compared to females of the same age, male patients over 40 years of age are more vulnerable to MDRTB. this was not part of the research objectives, emphasis should not be placed on this as either conclusion or recommendation.