prophylaxis for Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae. Coated CVCs demonstrated a reduction of up to 70-90% of Gram-negative bacteria growth when compared to the (clean) control catheter. In addition, photothermal ablation (PHAB) of coated catheters already contaminated with bacterial biofilm (CVC-BF) can optionally be triggered to eliminate biofilm formations. CVC-BF cultured for 96 h after a PHAB treatment carried out for 5 min at 80 ° C resulted in the reduction of the viability of the bound bacteria in 71 to 88%.
RESUMO-A leishmaniose é uma zoonose largamente disseminada no Brasil. O presente trabalho tem como principal objetivo estudar o processo de eletropolimerização do sistema NPsFe 3 O 4 / Quit/PANI frente amostras de genoma e soro de cães infectados com leishmaniose. A avaliação do sistema foi realizada através da técnica eletroquímica de voltametria cíclica para caracterizar as propriedades elétricas do sistema NPsFe 3 O 4 / Quit/PANI-Primer Leish. Os resultados mostram que o sistema sensor foi capaz de reconhecer as amostras de genomas e de soro dos cães infectados, em várias concentrações, sendo observada uma diminuição da resposta amperométrica total do sistema. Mostrando assim que o sistema NPsFe 3 O 4 / Quit/PANI-Primer Leish é viável para detecção da leishmaniose. Palavras chave-biossensor, voltametria, impedância, leishmaniose ABSTRACT-Leishmaniasis is a widespread zoonosis in Brazil. The present work has as main objective to study the process of electropolymerization of the NPsFe 3 O 4 / Quit / PANI system against genome and serum samples from dogs infected with leishmaniasis. The evaluation of the system was performed by the electrochemical technique of cyclic voltammetry to characterize the electrical properties of the NPsFe 3 O 4 / Quit / PANI-PrimerLeish system. The results show that the sensor system was able to recognize the genomic and serum samples of the infected dogs at various concentrations, with a decrease in the total amperometric response of the system. Thus showing that the NPsFe 3 O 4 / Quit / PANI-PrimerLeish system is feasible for detection of leishmaniasis.
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