EFE in children is rare; seen with broom stick and needle injuries, if managed early recovers optimum vision.

INTRODUCTION: Staphylococcus aureus causes a wide range of infections including skin and soft tissue infections to life-threatening systemic infections like sepsis, endocarditis. This study ais to evaluate the antimicrobial susceptibility pattern of S.aurues among various clinical specimens. METHODS: The study included 326 S.aurues, isolated from various clinical specimens which were subjected to antimicrobial susceptibility testing as per CLSI guidelines. RESULTS: Among the 326 isolates, the highest were from pus specimens (47.85%), and was from Orthopaedics department (28.53%). Among the isolates, 219 (67.17%) were Methicilin resistant. All isolates were sensitive to Vancomycin, and all urine isolates were sensitive to Nitrofurantoin. The highest resistance was towards Penicillin (87.42%), Erythromycin (85.28), and Ciprooxacin (83.13%). CONCLUSION: The most effective way to prevent MRSA infection in every hospital is by performing continuous surveillance of antibiotic resistance and by following an effetive antibiotic policy.

Background: Ocular infections are one of the major causes of visual impairment around the world. Infections can either be due to single microbe or polymicrobial. it is essential to know the specic etiology of the infection for the effective management of ocular infections. This study aims to identify microbes responsible for common ocular infections and to determine its antibiotic susceptibility to commonly used antibiotics used in clinical practice. Clinical Methods: A hospital based cross sectional study included 290 patients attending the ophthalmology department of a tertiary care hospital. After a thorough clinical examination samples were taken and were subjected to Grams' stain, culture methods, biochemical tests for the identication of the microbe. Antibacterial susceptibility test was performed using Kirby Bauer disc diffusion method. Results: Among 290 patients, the common clinical conditions include conjunctivitis 108 (37.24%), keratitis 37 (12.76%), dacryocytitis 53 (18.28%), blepharitis 52 (17.93%), trauma 24 (8.28%), infective uveitis 10(3.45%) and endophthalmitis 6(2.07%). Among the total ocular infections 146(50.34%) were positive for culture. Among the total isolated, 110(75.34%) were Gram positive and 36(24. 66%) were Gram negative. The Gram positive bacteria isolated showed highest sensitivity to ciprooxacin (86.36%) followed by gentamycin (82.72%) and clindamycin (80%). The Gram negative bacteria showed high resistance to tetracycline 7(19.44%), followed by amoxicillin-clavulanic acid (30.56%). Conclusion: The most common ocular infection is conjunctivitis followed by dacryocystitis which is most commonly caused by Staphylococcus aureus, which showed high resistance to Amoxcillin, Tetracycline and Erythromycin. To prevent the emergence of antimicrobial resistance, it is necessary to perform antimicrobial susceptibility testing before initiating antibiotics in clinical practice.