Background: Diabetes mellitus (DM), sometimes known as diabetes, is a collection of metabolic illnesses defined by a persistently high blood sugar level. Frequent urination, increased thirst, and increased appetite are common symptoms. In all nations, DM complications have become a serious public health issue. Objectives: A hospital-based study, a prospective observational study was conducted among diabetic patients with diabetic foot ulcers at Government Medical College (GMC), Nizamabad. From September 2020 to October 2021 Materials and Methods: To calculate the sample size, a total population of 450 patients with type 2 DM diagnosed during the 6-month study period was considered. DFU patients were studied clinical characteristics of diabetic foot ulcer patients among diabetes mellitus patients, and risk factors and outcomes of diabetic foot ulcer. Results: 100 Diabetic foot ulcers (DFU) patients were admitted to the GMC throughout the research period, with 61 (61%) of them being male. The age group between 18 to 78 years, with an average of 58.9 ± 9.56 years. The following groups had higher frequencies among participants: married 56 (56 %), schooling up to primary school 36 (36%). Type 2 diabetes mellitus affected 59 of them (59%). Amputations were performed on 35 (35%) of the patients, whereas 65 (65%) had no amputation. The most generally recommended antibiotic for the treatment of DFU was cloxacillin + metronidazole 39 (39%), followed by ceftriaxone. Furthermore, diabetic foot ulcer patients with neuropathy were more likely to require amputation (AOR = 1.6250; 95 % CI: 0.6479, 4.0756) than diabetic foot ulcer patients without neuropathy. Conclusion: Blood glucose level, higher body mass index, inappropriate antibiotics use, neuropathy and advanced grade of diabetic foot ulcer were independent predictors of amputation. Thus, a focus on weight loss, treating hyperglycemia, and prescribing suitable antibiotics for patients with neuropathy and advanced diabetic foot ulcers might reduce the unfavorable consequences of diabetic foot ulcers.
Background: Fournier's gangrene (FG) is fast-spreading necrotizing gangrene that affects the perineum, perianal, and genital regions, but spares the testicles, bladder, and rectum due to their independent blood supply from the aorta. The purpose of this research is to share our experience managing 32 cases. Patients and method: Between April 2018 and May 2022, researchers from Government Medical College in Nizamabad conducted a prospective cross-sectional study of patients with FG. During the study period, all individuals diagnosed with FG and treated for it were included. Age, sex, hospital stay, premorbid conditions, mobility, mortality, laboratory examinations, and therapies performed are among the data collected from these. Results: A total of 38 patients were seen throughout the study, with four patients being eliminated due to missing data, leaving 32 patients for the final analysis. With a male to female ratio of 15:1, there were 30 (93.75%) males and 2 (6.25%) females.
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