An analysis is performed to study the shear stress, the couple-stress and heat transfer characteristics of a laminar mixed convection boundary layer flow of a micropolar fluid past an isothermal permeable plate. The governing nonsimilar boundary layer equations are analyzed using the (i) series solution for small ?, (ii) asymptotic solution for large ? and (iii) primitive-variable formulation and the stream function formulation are being used for all ?. The effects of the material parameters, such as, the vortex viscosity parameter, K, and the transpiration parameter, s, on the shear stress, the couple-stress and heat transfer have been investigated. The agreement between the solutions obtained from the stream-function formulation and the primitive-variable formulation is found to be excellent.

ABSTRACT:Mixing process is widely used in pharmaceutical industry to blend different API as well as additives to prepare solid dosage formulations. If mixing is not done properly there is always chance of dose variation and content uniformity variations. Due to this, the present paper deals with the study of the effect of mixing time, speed and % of one compound in another on the effectiveness of the process. Statistical analysis technique was used to understand the interaction effect of variables instead of one factor at a time. A 2 3 factorial design was applied to investigate the combined effect of three formulation variables, time (A), mixing speed (B) of and the % amount of diclofenac sodium (C) used. The mixing index (MI) taken as responses (Y). Polynomial equations were used to relate each response to the factors affecting it. Counter plots and response surface plots were drawn and an optimum formulation was selected using the desirability function.