The in vitro activity of cefoxitin was compared with those of metronidazole and clindamycin against 322 strains of anaerobic bacteria collected from several hospitals during 1982 and tested by an agar dilution method. Metronidazole and cefoxitin inhibited at least 89%o of strains tested, whereas clindamycin was less active.Continued updating of the susceptibility of recent clinical isolates and follow-up in changes of antibiotic patterns are periodically necessary in every country. When the same methodology is retained, an increase in resistance levels or local differences can be demonstrated (28,29). Considering the lack of such studies in France, our purpose was to determine the antibiotic susceptibility of anaerobic bacteria, using the first data available by the reference method of Sutter et al. (25)
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