A system for recording large‐amplitude discrete extremely low frequency atmospherics (ELF “events” or “Q bursts”) produced by global lightning activity is described. The location of the source lightning flashes for some 261 events has been deduced from these data. In the data set, about 75% of the signals were produced by positive flashes and 25% were produced by negative flashes. The analysis technique depends on the fact that in the lower ELF band (5–45Hz), signals can be detected which have made multiple circulations of the globe. The range of the sources was found by modelling the data using a least squares fit to the complex wave impedance computed using the well‐established propagation theory applicable to the Earth‐ionosphere spherical‐shell waveguide. The source bearings were deduced from two orthogonal components of the magnetic field vector using the usual goniometric technique. The data show that the majority of the sources of ELF events are located in low‐latitude regions, an average of 7.4 Mm away from the observing station situated in the UK. The use of such a system to monitor worldwide thunderstorm activity, so far as this relates to ELF events observed in the band 5–45 Hz, is demonstrated.

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Oncolytic virotherapy represents a promising approach for treating recurrent and/or drug-resistant ovarian cancer. However, its successful application in the clinic has been hampered by rapid immune-mediated clearance, which reduces viral delivery to the tumor. Patient-derived mesenchymal stem cells that home to tumors have been used as viral delivery tools, but variability associated with autologous cell isolations limits the clinical applicability of this approach. We previously developed an allogeneic, clonal neural stem cell (NSC) line (HB1.F3.CD21) that can be used to deliver viral cargo. Here, we demonstrate that this NSC line can improve the delivery of a thymidine kinase gene-deficient conditionally replication-competent orthopoxvirus, CF33, in a preclinical cisplatin-resistant peritoneal ovarian metastases model. Overall, our findings provide the basis for using off-the-shelf allogeneic cell-based delivery platforms for oncolytic viruses, thus providing a more efficient delivery alternative compared with the free virus administration approach.