Glycopolymers are synthetic-carbohydrate-containing materials capable of interacting and binding to specific targeting lectins, which are crucially important in many biologically active processes. Over the last decade, advances in synthetic chemistry and polymerization techniques have enabled the development of sequence and architecturally controlled glycopolymers for different types of bioapplications, such as drug delivery and release purposes, gene therapy, lectin-based biosensors, and much more in the future. These precision glycopolymers are able to mimic structural and functional features of the naturally existing glycocalyx. Furthermore, self-assembled glycopolymers could enhance specific and selective recognition properties on multivalent scaffolds in glycoscience. This mini-review will focus on production methods and recent advances in precision synthesis and self-assembly of glycopolymers. Additionally, possible contributions of single-chain folding in glycopolymers will be discussed as a future prospect.

Levulinic acid is a multipurpose platform chemical that is currently used in a wide variety of applications.

From drug delivery to nanoreactors and protocells, polymersomes have gained considerable interest from researchers due to their novel applications. However, one of the main challenges is the selection of the...

Bildet eine Kette! Vielblock‐Glykopolymere aus Monomeren mit Mannose‐ (M, siehe Schema), Glucose‐ und Diethylenglycolethylether(D)‐Substituenten wurden mit kontrollierten Sequenzen synthetisiert. Die hoch monodispersen Glykopolymere wurden auf die Bindung und Inhibition von DC‐SIGN, einem für die HIV‐Infektion bedeutsamen Protein, hin getestet.