The classic problem of alpha absorption is discussed in terms of the quantitative determination of the activity of "weightless" alpha sources and the specific alpha activity of extended sources accounting for absorption in the source medium and the window of a large area ZnS(Ag) scintillation detector. The relationship for the expected counting rate gamma of a monoenergetic source of active area A, specific alpha activity C, and thickness H that exceeds the effective mass density range Rs of the alpha particle in the source medium can be expressed by a quadratic equation in the window thickness x when this source is placed in direct contact with the window of the ZnS(Ag) detector. This expression also gives the expected counting rate of a finite detector of sensitive area A exposed to an infinite homogeneous source medium. Counting rates y obtained for a source separated from a ZnS(Ag) detector by different thicknesses x of window material can be used to estimate parameter values in the quadratic equation, y = a + bx + cx2. The experimental value determined for the coefficient b provides a direct estimation of the specific activity C. This coefficient, which depends on the ratio of the ranges in the source medium and detector window and not the ranges themselves, is essentially independent of the energy of the alpha particle. Although certain experimental precautions must be taken, this method for estimating the specific activity C is essentially an absolute method that does not require the use of standards, special calibrations, or complicated radiochemical procedures. Applications include the quantitative determination of Rn and progeny in air, water, and charcoal, and the measurement of the alpha activity in soil and on air filter samples.
A dosimetric model is proposed for the gastrointestinal tract based upon the physiological model of EVE (1966a). A general equation describing the kinetics of linear first order phenomena is applied to obtain the burden of radionuclides or disintegrations in the contents of the various segments of the GI tract. The model gives equations for the calculation of the "dosimetric" average dose equivalent and dose equivalent rate to an entire segment as well as instantaneous values at any location within a given segment as applicable to single or continuous uptakes of parent and daughter radionuclides. Allowance is made for both the absorption of radionuclides as well as mass from the contents of all segments; although, this is not always considered significant. The model permits the determination of the quantities of a radionuclide absorbed into the blood, the ratio of daughter to parent disintegrations and the maximum to average dose equivalent rate in a particular segment of the GI tract. Numerical examples are given for various intakes. Maximum permissible daily ingestion rates of fictitious single soluble and insoluble radionuclides with an effective energy term of unity in all segments are given over a large range of half-lives and are compared to values calculated on the basis of current ICRP recommendations. It is proposed that ratios of the maximum to dosimetric average dose equivalent rate be used to define a distribution factor to take into account relatively high dose rates at particular locations within a segment of the GI tract.All equations have been derived using the more fundamental units of atoms or disintegrations and disintegration rates rather than the more popular pCi and pCi-day units. The former units are more fundamentally related to dosimetric quantities of interest.
The chi-square statistic has many scientific applications, including the evaluation of variance in counting data and the proper functioning of a radiation counting system. This paper provides a discussion of the fundamental aspects of the chi-square test using counting data. Practical applications of the chi-square statistic are discussed, including the estimation of extra-Poisson variance and dead time for a counting system. The consequences of passing or failing the chi-square test are discussed regarding the proper estimator for the population variance of the counting data. Example scenarios are used to provide insight into the applications of the chi-square statistic and the interpretation of values obtained in hypothesis testing.
This paper describes a way of obtaining and gives applications of intake retention functions. These functions give the fraction of an intake of radioactive material expected to be present in a specified bioassay compartment at any time after a single acute exposure or after onset of a continuous exposure. The intake retention functions are derived from a multicompartmental model and a recursive catenary kinetics equation that completely describe the metabolism of radioelements from intake to excretion, accounting for the delay in uptake from compartments in the respiratory and gastrointestinal tracts and the recycling of radioelements between systemic compartments. This approach, which treats excretion as the 'last' compartment of all catenary metabolic pathways, avoids the use of convolution integrals and provides algebraic solutions that can be programmed on hand held calculators or personal computers. The estimation of intakes and internal radiation doses and the use of intake retention functions in the design of bioassay programs are discussed along with several examples.
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