MCC is an aggressive neuroendocrine tumour of the elderly. Wide surgical excision is the recommended treatment. Lymph node dissection, adjuvant radiotherapy and chemotherapy decrease regional recurrences but have not been demonstrated to increase survival. Immunohistochemically, MCC is an epithelial tumour with neuroendocrine features.
Annular elastolytic giant cell granuloma (AEGCG) is rare granulomatous dermatoses of uncertain pathogenesis. It usually presents itself in adults over the age of 40. Clinically characterized by annular plaques with well defined erythematous borders with a normal or atrophic center in a polycyclical pattern which usually presents itself in photoexposed areas of the skin. It is necessary to have histological study of the lesions for the diagnosis. In which you can see a granulomatous reaction with elastolysis, phagocytosis of elastic fibers and multinucleated giant cells with absence or reduction of elastic fibers. We will present a case of a 73 year old woman with AEGCG with the main differential diagnosis being discoid lupus.
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