<p>In 2020, many countries implemented lockdowns to control the spread of the novel coronavirus disease (COVID-19), leading to reported decreases in anthropogenic CO<sub>2</sub> emissions based on bottom-up estimates. Some studies reported that the resulting atmospheric CO<sub>2</sub> changes were below the detection limit of current observing systems on the ground or in space. We quantify CO<sub>2</sub> emissions from Europe&#8217;s largest fossil fuel burning power plant before and during lockdown using space-based CO<sub>2</sub> observations from NASA&#8217;s Orbiting Carbon Observatory (OCO) 2 and 3 missions. The results show clear emission reductions of >20% in April 2020, demonstrating the ability of space-based CO<sub>2</sub> observations to quantify emission reductions at the facility level. This research reinforces the value of space-based CO<sub>2</sub> data for verifying future CO<sub>2</sub> emission reductions expected from climate change mitigation policies and the importance of monitoring emissions at sub-national scales.</p>
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