Nanohybrids of enriched (6,5) single-walled semiconducting carbon nanotubes (E-SWCNTs) and porphyrin can be used synergistically as photodynamic therapy (PDT) agents. The efficiency of different porphyrins within the nanohybrids was investigated and compared with results obtained from porphyrins in previous studies. Reactive oxygen species singlet oxygen (1)O2 and for the first time hydroxyl radical ˙OH generation by the nanohybrids under illumination were detected by electron paramagnetic resonance using spin trapping molecules TEMP and PBN. Based on the analysis, we improve the modelling of charge transport within the nanohybrids, which is also detected by Raman scattering. It is shown that the 5,10,15,20-tetrakis(4-trimethylammoniumphenyl)porphyrin [H2TTMAPP(OTs)4] and E-SWCNT form very efficient nanohybrids for PDT applications in the visible spectral range.
Caso clínico Resumo O objetivo deste relato de caso foi estabelecer protocolo de estimulação via marca-passo diafragmático, pela equipe de fisioterapia do Hospital Universitário Pedro Ernesto, visando desmame da ventilação mecânica invasiva de uma paciente com lesão medular alta internada na Unidade de Terapia Intensiva há 13 anos por dependência de ventilação artificial. Verificou-se aumento do volume corrente durante a estimulação e também aumento em cinco vezes na pressão inspiratória máxima comparado ao valor inicial. Entretanto, o treino foi interrompido no 40º dia devido à instalação de neuromielite óptica que a fez perder condução dos nervos frênicos momentaneamente. Descritores: Marca-passo diafragmático; Nervo frênico; Lesão medular cervical; Desmame do respirador; Ventilação mecânica invasiva; Fisioterapia respiratória.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.