Behcet disease (BD) and recurrent aphthous stomatitis (RAS) are systemic inflammatory diseases, but the exact pathogenesis of both the diseases is unknown. Mean platelet volume (MPV) is an indicator of platelet activation. The aim of this study was to investigate the MPV levels in patients with BD, RAS, and healthy participants. A total of 61 patients with BD, 60 patients with RAS, and 60 healthy controls were included in this study. The MPV levels and erythrocyte sedimentation rate in patients with BD and RAS groups were significantly higher than the control groups (P < .001). In the BD group as well as in the RAS group, the disease activity does not affect the levels of MPV. The MPV levels may be used as a cheap and feasible diagnostic marker in patients with BD and RAS. Nevertheless, the MPV does not have a predictive value in differentiating the diagnosis of BD and RAS.
BackgroundAndrogenetic alopecia is one of the most common forms of hair loss. Alopecia
areata is a common autoimmune disorder which causes hair loss. It has been
previously reported that both alopecia disorders can have negative effects
on quality of life. However, only a few studies have compared the effects of
the two disorders.ObjectiveThe aim is to show the impact of alopecia on patients' quality of life and
compare patients with androgenetic alopecia and alopecia areata.Methods82 androgenetic alopecia and 56 alopecia areata patients were recruited. All
patients were evaluated with the Hairdex scale and dermatology quality of
life instrument in Turkish (TQL), and the scores were statistically compared
according to age, sex, employment and education status, and severity of
illness in the two groups. Also, female patients were statistically
evaluated according to whether they wore headscarves.ResultsAndrogenetic alopecia patients had significantly higher total Hairdex scores
in terms of emotions, functioning, and symptoms, while self-confidence was
significantly higher in the alopecia areata patients. No significant
differences were found in stigmatization or TQL scores between groups. The
Hairdex scale and TQL scores did not show differences between the groups in
terms of wearing headscarves.Study limitationsThe validity and reliability of the Hairdex index have not been established
in Turkey.ConclusionsBased on the Hairdex scale, our findings revealed that androgenetic alopecia
patients are more affected by their disorder than alopecia areata patients.
Although androgenetic alopecia is common and neither life-threatening nor
painful, it is a stressful disorder with increased need for improvement in
the patient's quality of life.
It seems that nail psoriasis constitutes a risk factor not for onychomycosis, but specifically for dermatophytic nail infections. Because of the similar therapeutic results in each group, different antifungal treatment protocols may not be needed in psoriasis. However, to confirm this, new comprehensive studies are necessary.
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