<p>Background: Excess iron levels and low hemoglobin (Hb) levels are one of the complications of Beta-Thalassemia. The implementation of education using <em>WhatsApp</em> is expected to increase parental knowledge of the illness and children to adhere to iron chelation therapy.</p><p> </p><p>Objective: To identify the effect of the implementation of education using <em>WhatsApp</em> through the SKEDit application compared to using booklets on parental knowledge and medication adherence in pediatric patients with thalassemia.</p><p> </p><p>Method: The study was quasi-experimental using pre and post-test with control group.  The total sample was 61 respondents with purposive sampling technique. Parental knowledge was measured using a Parental knowledge about Thalassemia questionnaire and the level of adherence was measured using an indirect method known as 'Pill Count'. The data were then analyzed using the Mann whitney and wilcoxon test.</p><p> </p><p>Results: There was a significant difference in the level of knowledge in the pretest and posttest on the intervention group (p: 0.001) and the pretest and posttest in the control group (p: 0.001). There was a significant difference in the level of adherence of the pretest and posttest in the intervention group (p: 0.028). There was no significant difference in the level of adherence of the pretest and posttest in the control group (p: 0.214). There was no difference in the level of knowledge between the two groups (p: 0.994). There was no difference in the level of adherence between the two groups (p: 0.987).</p><p> </p><p>Conclusion: Providing education using WhatsApp through the SKEDit application and also booklets both effectively increase the level of parental knowledge and medication adherence of pediatric patients with thalassemia.</p>

Introduction. Hypothermia is low-body temperature (less than 36,5°C) that can caused morbidity and mortality in premature newborn and or low-birth weight newborn. Plastic has often been used to prevent the heat loss in newborn.The aim of study was to measure the effectiveness of plastic bag wrap to prevent hypothermia in preterm and low-birth weight infant. Method. The study design was quasy expertment non randomized pretest-posttest with control group. In intervention group, there were five premature and or low-birth weight newborns that were being wrapped with special design plastic bag from neck to toe after been given neonatal standard care protocol. While, in control group, there were six newborns with the same baseline criteria as intervention group without plastic bag wrap. The measurement of body temperature used digital thermometer on babies’ axilla before and after one-hour intervention. Data analysis used t test. Result. The result showed there was almost significant difference in body temperature in newborn before and after intervention (pvalue 0.056). Discussion. Plastic bag wrap is effective to prevent hypothermia in premature and or low-birth weight newborn as much as 60% with body temperatur changes +0.4°C. Keywords: Plastic Bag Wrap, Hypothermia, Preterm, Low-Birth weight