All 10% HP bleaching systems showed similar whitening after a 14-day use. However, the strips and prefilled disposable trays produced lower intensity of tooth sensitivity than the conventional bleaching tray system. The prefilled disposable tray produced lower risk of gingival irritation when compared to the conventional bleaching tray.

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The role of dentin cleaning is to remove debris that may impair adaptation and marginal sealing, quantitatively reducing microorganisms. The aim of this study was to investigate through scanning electron microscopy (SEM) the morphology of the dentin surface, cut and treated with copaiba oil emulsions (CO) and suspension of ethanol extract of propolis (EP). Twenty four upper pre-molars teeth, divided into eight groups (n=3), were used: G1: no cleaning, G2: air/water spray, G3: 10% CO, G4: 10% CO + A, G5: 30% CO, G6: 30% CO + A, G7: 1% EP, G8: 2% Chlorhexidine. The specimens were dentin discs (1 mm Ø). The SEM photomicrographs were classified and the results were: G1 - Debris dentin on the entire image / countless microorganisms, G2 and G7 - 50-100 debris / countless microorganisms and G3, G4, G5, G6 and G8 - 0-50 debris / countable microorganisms (50-100 colonies).Conclusion:The present results suggest that copaiba oil emulsions (CO) and suspension of ethanol extract of propolis (EP) have feasibility to be used as bioactive dental cleaning agents.

This study analyzed the effect of prior application of copaiba oil (CO) emulsions as a dentin cleaning substance on microleakage and microtensile adhesive strength. Twenty-five premolars and sixty-four molars were used for microleakage and microtensile assays. For the microleakage assays, specimens with standard class V cavities were divided (n = 5), according to the tested CO emulsions: CO10%X, CO10%Y, and CO10%Z, as well as chlorhexidine 2% (CHX) and distilled water (DW), as positive and negative controls, respectively. Restorations were performed using the Adper Single Bond® and/or Clearfil SE Bond® systems. Cervical, occlusal, distal and mesial sections were assessed for tracer penetration degree at the composite/tooth interface. For the microtensile assay, healthy molars were divided into sixteen groups, in which artificial caries were induced in half of the groups. Dentin surfaces were treated with CO10%X and CO10%Y, CHX and DW. Microtensile bond strength was measured by fixing each sample to the plate of a universal testing machine operated at a speed of 0.5 mm/minute until failure. Dentin treated with CO10%X showed a lower infiltration rate than dentin treated with the other CO emulsions, CHX2% and DW. According to the microtensile assay, both healthy and affected dentin treated with CO10%X and Adper Single Bond® adhesive system presented higher adhesive strength. CO emulsion, used as a dentin biomodifier, interfered positively in microleakage and improved adhesive strength after acid etching in the Adper Single Bond® adhesive system, or before applying the Clearfil SE Bond® self-etching system.

Nas últimas décadas, houve um aumento no interesse dos profissionais de saúde acerca do uso e do conhecimento de medicamentos fitoterápicos. Entre estes, destaca-se o óleo de copaíba, por suas atividades antimicrobiana, analgésica e anti-inflamatória. Para analisar in vitro a atividade antiinflamatória das emulsões de Copaífera em macrófagos, quantificando a produção de radicais livres, utilizou-se uma cultura de macrófagos da cepa 264,7, cultivada no Meio Eagle Dulbecco Modificado completo, suplementada com 10% soro fetal bovino inativado e penicilina/estreptomicina (100 UI / mL/100 μg/mL), sendo mantidos em forno úmido a 37oC. Após a tripsinização, os macrófagos foram contados em câmara de Neubauer e submetidos à emulsão de fitoterápicos. O anti-inflamatório dexametasona (20 μg /mL) foi utilizado como padrão-ouro para comparar os resultados. A liberação de óxido nítrico foi quantificada pela produção de nitrito na reação colorimétrica de Griess. Para cada volume de 100 μL dos sobrenadantes previamente coletados dos desafios celulares, foram adicionados 100 μL de reagente Griess (Sigma Aldrich), que foram incubados em temperatura ambiente por 30 minutos Em seguida, a absorbância (540nm) foi determinada em um espectrofotômetro. Os resultados foram analisados por médias ± desvios-padrão e submetidos aos testes de Kolmogorov-Smirnov, Tukey e Dunnett. Os autores concluíram que o óleo de copaíba e suas emulsões reduzem significativamente a quantidade de óxido nítrico produzido pelos macrófagos durante o processo inflamatório.