The CanScreen5 project is a global cancer screening data repository that aims to report the status and performance of breast, cervical and colorectal cancer screening programs using a harmonized set of criteria and indicators. Data collected mainly from the Ministry of Health in each country underwent quality validation and ultimately became publicly available through a Web-based portal. Until September 2022, 84 participating countries reported data for breast (n = 57), cervical (n = 75) or colorectal (n = 51) cancer screening programs in the repository. Substantial heterogeneity was observed regarding program organization and performance. Reported screening coverage ranged from 1.7% (Bangladesh) to 85.5% (England, United Kingdom) for breast cancer, from 2.1% (Côte d’Ivoire) to 86.3% (Sweden) for cervical cancer, and from 0.6% (Hungary) to 64.5% (the Netherlands) for colorectal cancer screening programs. Large variability was observed regarding compliance to further assessment of screening programs and detection rates reported for precancers and cancers. A concern is lack of data to estimate performance indicators across the screening continuum. This underscores the need for programs to incorporate quality assurance protocols supported by robust information systems. Program organization requires improvement in resource-limited settings, where screening is likely to be resource-stratified and tailored to country-specific situations.

A Odontologia, assim como diversas outras áreas da saúde, vem evoluindo consideravelmente não só no que diz respeito às técnicas, mas também na forma de enxergar o novo modelo de mercado de trabalho cada vez mais concorrido. O empreendedorismo tem forte impacto social juntamente aos conhecimentos sobre marketing que auxiliam no destaque desses profissionais. Este estudo teve como objetivo verificar a diferença do perfil empreendedor e conhecimentos de marketing dos discentes do Curso de Graduação em Odontologia da Universidade de Vassouras, entre as turmas de terceiro período, quinto período e sétimo período, por meio de uma pesquisa descritiva do tipo transversal. Os dados foram coletados a partir de um formulário do Google Forms, contendo questionário para avaliação do perfil empreendedor e outro questionário a respeito de conhecimento de estratégias de marketing e sua importância para a vida profissional. Esses dados foram tabulados e submetidos à análise estatística descritiva. Participaram do estudo 64 estudantes dos três períodos. Em relação ao perfil empreendedor, os alunos de ambos os períodos foram classificados por “muitas características empreendedoras” de acordo com a pesquisa. Sobre conhecimentos de marketing, os alunos afirmaram conhecer e acreditar na importância do marketing na vida profissional. Com isso, mostrou-se o quão apto estes discentes dos períodos citados estão para engajar no mercado de trabalho.

Food innovation and entrepreneurship are important topics in graduate food studies. Students should be challenged to promote an innovative attitude towards their future career in the food industry sector, as professionals working in a small and medium-sized enterprise, or in a large multinational company, or even as entrepreneurs with their own working projects. The present case study shows a curricular unit of a master course that intends to integrate the knowledge on new and sustainable technologies and products, based on seminars of experts on hot topics, on visits to food industry enterprises and market expositions and on the development of a state-of-the-art report about an emergent or novel food technology or product with oral presentation. Hot topic seminars included edible coatings, bioprocessing, allying tradition and innovation in food products, new convenience foods, challenging tests, and new clean and sustainable processes. Entrepreneur alumni lectures were also promoted allowing exchange of experiences. Visits included a high pressure technology unit of a food industry, an innovation and development department of a food industry, an entrepreneurship centre and a food exhibition. A satisfaction survey was made, through the response of a questionnaire by the students, proving the effectiveness and success of this unit course framework. A SWOT analysis was carried out to gain a better understanding of the strengths, weaknesses, opportunities, and threats involved in the curricular unit objectives.

Introduction: Breast cancer (BC) is a public health problem in developing countries, including Cape Verde. Immunohistochemistry (IHC) is the gold standard technique used for BC phenotypic characterisation to support efficient therapeutic decisions. However, IHC is a demanding technique that requires knowledge, trained technicians, expensive antibodies and reagents, controls, and results validation. The low number of cases in Cape Verde increases the risk of expiring the validity of the antibodies, and manual procedures often jeopardise the quality of the results. Thus, IHC is limited in Cape Verde, and an alternative technically easy solution is needed. A point-of-care messenger RNA (mRNA) STRAT4 BC assay to assess estrogen (ER), progesterone (PR), hormone growth factor 2 receptor (HER2), and Ki67, using the GeneXpert platform, has been recently validated on tissues from internationally accredited laboratories, showing excellent concordance with IHC results.To assess whether this technology can be implemented in Cape Verde to guide BC treatment we decided to study the level of agreement between the findings yielded by BC STRAT4 and the results are the same cases obtained by IHC.Methods: Formalin-fixed and paraffin-embedded (FFPE) tissue samples from 29 Cabo Verdean BC patients diagnosed in Agostinho Neto University Hospital were analysed by applying IHC and BC STRAT4 assay. The time between sample collection and pre-analytic procedures is unknown. All the samples were pre-processed in Cabo Verde (fixed in formalin and embedded in paraffin). IHC studies were performed in referenced laboratories in Portugal. STRAT4 and IHC result concordance was assessed by calculating the percentage of results agreement and Cohen's Kappa (K) statistics.Results: STRAT4 assay failed in 2 out of the 29 analysed samples. Of the 27 successfully analysed samples, STRAT4/IHC results for ER, PR, HER2, and Ki67 were concordant in 25, 24, 25, and 18 cases, respectively. Ki67 was indeterminate in three cases, and PR was indeterminate once.The percentage of agreement between STRAT4 and IHC results for ER, PR, HER2, and Ki67 was 92.59%, 92.31%, 92.59% and 81.82%, respectively. The Cohen's K statistic coefficients for each biomarker were 0.809, 0.845, 0.757 and 0.506, respectively.Conclusions: According to our preliminary results, a point-of-care mRNA STRAT4 BC assay may be an alternative in laboratories unable to pro-vide quality and/or cost-efficient IHC services. However, more data and improvement on sample pre-analytic processes are required to implement this BC STRAT4 Assay in Cape Verde.