Objective: To investigate whether there is any risk of seeding by neoplasic cells along biopsy tracks and to study local histological abnormalities. Methods: This was a prospective study on biopsy tracks in patients who underwent operations due to malignant musculoskeletal tumors between April 2006 and April 2007. Results: Neoplasic cell implantation occurred in 32% of the tracks.The most common histological abnormalities in positive cases were classified as severe fibrosis, mild inflammatory component and severe neovascularization. Conclusion: We suggest that traditional oncological resection of the track should be carried out together with excision of the specimen.

SUMMARyGiant Cell Tumor (GCT) is a benign tumor, with a recurrence rate of about 20% -34% of the cases. It is usually located at long bone epiphysis. The objective of this study is to report a GCT case in a vertebra, which was early diagnosed as Aneurysmal Bone Cyst (ABC), and to discuss potential differential diagnosis, correlating them to patterns shown on imaging tests. This patient is a 37 year-old female, with clinical picture of pain in spine and paraparesis that started two months earlier.An early diagnosis of ACB was delivered. At X-ray, the injury was lithic, with erosion and cortical destruction. Tomography and resonance showed a cystic and hemorrhagic injury, extending to soft parts. Slides review and the analysis of dried surgical matter submitted to HE and immunohistochemical staining with p53 marker allowed for GCT diagnosis. Many benign lesions present with multi-nucleated giant cells. Imaging tests not always enable a conclusive diagnosis. A definite GCT diagnosis depends on anatomicopathological test, with careful evaluation of the stromal component and positive immunoexpression for p53 protein. Treatment is delivered as surgical resection, with wide margins, followed by instrumentation in cases of tumors located at spine.

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Tumor fibroso solitário extrapleural (TFS) é neoplasia mesenquimal rara, sendo que há menos de 40 casos descritos com localização em extremidades até o presente momento. Acomete preferencialmente pacientes na quinta década e não tem predileção por sexo. Relatamos um caso com os aspectos clínicos, radiológicos, histológicos e imunoistoquímicos característicos, discutindo a importância do diagnóstico diferencial com outros sarcomas.Pouco é conhecido sobre o comportamento biológico do TFS. Fatores de risco para menor sobrevida livre de metástases incluem: margens cirúrgicas comprometidas, tamanho maior que 10 cm e histologia maligna. Excisão completa é o tratamento recomendado.